SOLUBLE GUANYLATE CYCLASE ACTIVATORS
A compound of Formula (I): or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (cGMP) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The inven...
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| creator | SMITH CAMERON J LI HONG ORNOSKI OLGA A MIAO SHOUWU LIAO XIBIN WHITEHEAD ALAN WADDELL SHERMAN T GARFUNKLE JOIE GROEPER JONATHAN A CHEN YI-HENG BROCKUNIER LINDA L GUO JIAN RAGHAVAN SUBHAREKHA HAN XIAOQING PARMEE EMMA R ROSAUER KEITH CHANG JIANG STELMACH JOHN E |
| description | A compound of Formula (I): or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (cGMP) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula (I) or a pharmaceutically acceptable salt thereof. |
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The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula (I) or a pharmaceutically acceptable salt thereof.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130321&DB=EPODOC&CC=US&NR=2013072492A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20130321&DB=EPODOC&CC=US&NR=2013072492A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SMITH CAMERON J</creatorcontrib><creatorcontrib>LI HONG</creatorcontrib><creatorcontrib>ORNOSKI OLGA A</creatorcontrib><creatorcontrib>MIAO SHOUWU</creatorcontrib><creatorcontrib>LIAO XIBIN</creatorcontrib><creatorcontrib>WHITEHEAD ALAN</creatorcontrib><creatorcontrib>WADDELL SHERMAN T</creatorcontrib><creatorcontrib>GARFUNKLE JOIE</creatorcontrib><creatorcontrib>GROEPER JONATHAN A</creatorcontrib><creatorcontrib>CHEN YI-HENG</creatorcontrib><creatorcontrib>BROCKUNIER LINDA L</creatorcontrib><creatorcontrib>GUO JIAN</creatorcontrib><creatorcontrib>RAGHAVAN SUBHAREKHA</creatorcontrib><creatorcontrib>HAN XIAOQING</creatorcontrib><creatorcontrib>PARMEE EMMA R</creatorcontrib><creatorcontrib>ROSAUER KEITH</creatorcontrib><creatorcontrib>CHANG JIANG</creatorcontrib><creatorcontrib>STELMACH JOHN E</creatorcontrib><title>SOLUBLE GUANYLATE CYCLASE ACTIVATORS</title><description>A compound of Formula (I): or a pharmaceutically acceptable salt thereof, are capable of modulating the body's production of cyclic guanosine monophosphate (cGMP) and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. 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The invention furthermore relates to processes for preparing compounds of Formula I, or a pharmaceutically acceptable salt thereof, for their use in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and to pharmaceutical preparations which comprise compounds of Formula (I) or a pharmaceutically acceptable salt thereof.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | SOLUBLE GUANYLATE CYCLASE ACTIVATORS |
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