Compounds and Compositions as Protein Kinase Inhibitors

The present invention provides compounds of Formula I or II: wherein R1, R1b, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds of Formula (I) or (II) and pharmaceutical compositions thereof are useful for the treatment of B-Raf-associated diseases.

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Hauptverfasser: JIN JEFF (XIANMING), TELLEW JOHN, LIU ZHUOSHENG, ZHANG QIONG, POON DANIEL, COSTALES ABRAN Q, PECCHI SABINA, HUANG SHENLIN
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creator JIN JEFF (XIANMING)
TELLEW JOHN
LIU ZHUOSHENG
ZHANG QIONG
POON DANIEL
COSTALES ABRAN Q
PECCHI SABINA
HUANG SHENLIN
description The present invention provides compounds of Formula I or II: wherein R1, R1b, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds of Formula (I) or (II) and pharmaceutical compositions thereof are useful for the treatment of B-Raf-associated diseases.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Compounds and Compositions as Protein Kinase Inhibitors
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