PROTECTED MONOMERS AND METHODS OF DEPROTECTION FOR RNA SYNTHESIS

A nucleoside monomer that is protected by a thionocarbamate protecting group and contains one or more 2H, 13C, or 15N isotopes in the ribose and/or base part is provided, as well as a method for making a polynucleotide that uses the same. Also provided is a polynucleotide synthesis method that emplo...

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Hauptverfasser: DELLINGER DOUGLAS J, TIMAR ZOLTAN, SMART BRIAN PHILLIP, MYERSON JOEL, DELLINGER GERALDINE, SIERZCHALA AGNIESZKA B
Format: Patent
Sprache:eng
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