MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS

The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC tr...

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Hauptverfasser: LIU YAHUA, GONZALEZ, III JESUS E, GROOTENHUIS PETER DIEDERIK JAN, HADIDA-RUAH SARA SABINA, MILLER MARK THOMAS, OLSON ERIC R, VAN GOOR FREDERICK F, MAKINGS LEWIS RAY, SINGH ASHVANI KUMAR, CHAMBERS, III FRED, RADER JAMES ARVID
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creator LIU YAHUA
GONZALEZ, III JESUS E
GROOTENHUIS PETER DIEDERIK JAN
HADIDA-RUAH SARA SABINA
MILLER MARK THOMAS
OLSON ERIC R
VAN GOOR FREDERICK F
MAKINGS LEWIS RAY
SINGH ASHVANI KUMAR
CHAMBERS, III FRED
RADER JAMES ARVID
description The present invention relates to modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Regulator ("CFTR"), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
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recordid cdi_epo_espacenet_US2012184583A1
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
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