Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules

Novel derivatives of dihydro-1,4,2-oxathiazine and dihydro-1,4-dithiine oxides, more particularly, novel derivatives of dihydro-1,4,2-oxathiazine and dihydro-1,4-dithiine oxides that target cysteine residues of biomolecules of pharmacological importance are provided as pharmaceutically useful compou...

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Hauptverfasser: BREWER A. DAVID, OSIKA EWA, CHEE GAIK-LEAN, BROUWER WALTER G, HASINOFF BRIAN B
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creator BREWER A. DAVID
OSIKA EWA
CHEE GAIK-LEAN
BROUWER WALTER G
HASINOFF BRIAN B
description Novel derivatives of dihydro-1,4,2-oxathiazine and dihydro-1,4-dithiine oxides, more particularly, novel derivatives of dihydro-1,4,2-oxathiazine and dihydro-1,4-dithiine oxides that target cysteine residues of biomolecules of pharmacological importance are provided as pharmaceutically useful compounds, for example, as anticancer, antiinfectious, antigastric acid secretion, antiosteoporosic, and antiinflammatory agents.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules
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