Library of a Collection of Cells

The present invention relates to combinatorial gene expression libraries and methods for making these. Such libraries are useful in discovery of novel and/or enhanced metabolic pathways leading to the production of novel compounds for e.g., drug discovery and/or to the prosecution of known compounds...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SOERENSEN ALEXANDRA M.P. SANTANA, NIELSEN SOEREN V.S, GOLDSMITH NEIL
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to combinatorial gene expression libraries and methods for making these. Such libraries are useful in discovery of novel and/or enhanced metabolic pathways leading to the production of novel compounds for e.g., drug discovery and/or to the prosecution of known compounds in novel quantities or in novel compartments of the cells. The expression libraries in particular are composed of host cells capable of co-ordinated and controllable expression of large numbers of heterologous genes in the host cells.