USE OF APL-TYPE PEPTIDE FOR TREATING INTESTINAL INFLAMMATORY DISEASES AND TYPE 1 DIABETES

The present invention is related with the field of the medicine, particularly with the use of an APL peptide or its analogues derived from the human heat shock protein of 60 kDa, for the manufacture of a pharmaceutical composition for the treatment of Crohn's disease, ulcerative colitis and dia...

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Hauptverfasser:	DOMINGUEZ HORTA MARIA DEL CARMEN, FALCON CAMA VIVIANA, MENENDEZ VALDES IVON, LORENZO PEREZ NORAILYS, PADRON PALOMARES GABRIEL RAMON, BARBERA BETANCOURT ARIANA
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Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	DOMINGUEZ HORTA MARIA DEL CARMEN FALCON CAMA VIVIANA MENENDEZ VALDES IVON LORENZO PEREZ NORAILYS PADRON PALOMARES GABRIEL RAMON BARBERA BETANCOURT ARIANA
description	The present invention is related with the field of the medicine, particularly with the use of an APL peptide or its analogues derived from the human heat shock protein of 60 kDa, for the manufacture of a pharmaceutical composition for the treatment of Crohn's disease, ulcerative colitis and diabetes mellitus type 1. This peptide is biodistributed into the gastrointestinal tract and also promotes the induction of apoptosis in activated intestinal lamina propria and peripheral blood T cells of patients with Crohn's disease. Furthermore, this peptide induces apoptosis in mononuclear cells of patients with diabetes mellitus type 1.
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This peptide is biodistributed into the gastrointestinal tract and also promotes the induction of apoptosis in activated intestinal lamina propria and peripheral blood T cells of patients with Crohn's disease. 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subjects	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	USE OF APL-TYPE PEPTIDE FOR TREATING INTESTINAL INFLAMMATORY DISEASES AND TYPE 1 DIABETES
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