CONJUGATES FOR THE PREVENTION OR TREATMENT OF NICOTINE ADDICTION

The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment...

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Bibliographische Detailangaben
Hauptverfasser:	MEHELIC PAUL ROBERT, STEAD DAVID R, DAVIS HEATHER LYNN, THORN JENNIFER MARIE, PARSONS ERIN KRISTEN, GERVAIS DAVID P, KOLHE PARAG ASHOK, BROWN ALAN DANIEL, BHATTACHARYA KESHAB, ANASTASIOU NICKOLAS, FINNEMAN JARI ILMARI, MERSON JAMES R, JONES LYN HOWARD, MCCLUSKIE MICHAEL J, PRYDE DAVID CAMERON
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.