2-Aminopyrimidine modulators of the histamine H4 receptor

2-Aminopyrimidine modulators of the histamine H4 receptor

2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases,...

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Hauptverfasser: SAVALL BRAD M, SMITH DEBORAH M, RIZZOLIO MICHELE C, WEI JIANMAI, NEFF DANIELLE K, EDWARDS JAMES P, CAI HUI, VENABLE JENNIFER D, MANI NEELAKANDHA S, CHAVEZ FRANK, FITZGERALD ANNE E, LIU JING, WOLIN RONALD L
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator SAVALL BRAD M
SMITH DEBORAH M
RIZZOLIO MICHELE C
WEI JIANMAI
NEFF DANIELLE K
EDWARDS JAMES P
CAI HUI
VENABLE JENNIFER D
MANI NEELAKANDHA S
CHAVEZ FRANK
FITZGERALD ANNE E
LIU JING
WOLIN RONALD L
description 2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title 2-Aminopyrimidine modulators of the histamine H4 receptor
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