Substituted Azole Derivatives, Compositions, and Methods of Use

The present invention provides azole derivatives of Formula (I), methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I), and their use in treating human or animal disorders. The compounds of the invention can be useful as inhibitors of protein tyrosine phos...

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Hauptverfasser: XIE RONGYUAN, ANDREWS ROBERT C, POLISETTI DHARMA R, ARIMILLI MURTY N, SUBRAMANIAN GOVINDAN, QUADA, JR. JAMES C, YARRAGUNTA RAVINDRA R, MJALLI ADNAN M.M
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creator XIE RONGYUAN
ANDREWS ROBERT C
POLISETTI DHARMA R
ARIMILLI MURTY N
SUBRAMANIAN GOVINDAN
QUADA, JR. JAMES C
YARRAGUNTA RAVINDRA R
MJALLI ADNAN M.M
description The present invention provides azole derivatives of Formula (I), methods of their preparation, pharmaceutical compositions comprising the compounds of Formula (I), and their use in treating human or animal disorders. The compounds of the invention can be useful as inhibitors of protein tyrosine phosphatases and thus can be useful for the management, treatment, control, or the adjunct treatment of diseases mediated by PTPase activity. Such diseases include Type I diabetes and Type II diabetes.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Substituted Azole Derivatives, Compositions, and Methods of Use
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