AMINE COMPOUND AND USE THEREOF
It is intended to provide novel amine compounds which are efficacious against diseases such as infection with HIV virus, rheumatism and cancer metastasis. Namely, amine compounds represented by the following general formula (1): In a typical case, A1 and A2 represent each an optionally substituted m...
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| creator | YAMAZAKI TORU MATSUI RYO SUZUKI SHIGERU KIKUMOTO SHIGEYUKI YANAKA MIKIRO TAKEMURA YOSHIYUKI SAITOU ATSUSHI TAKAHASHI HARUKA HIROSE KUNITAKA KUMAKURA SEI ONO MASAHIRO |
| description | It is intended to provide novel amine compounds which are efficacious against diseases such as infection with HIV virus, rheumatism and cancer metastasis. Namely, amine compounds represented by the following general formula (1): In a typical case, A1 and A2 represent each an optionally substituted monocyclic or polycyclic aromatic heterocycle; W represents cyclic C3-10 alkylene, an optionally substituted monocyclic or polycyclic aromatic heterocycle, a monocyclic or polycyclic aromatic ring or a partly saturated polycyclic aromatic ring; X represents O, CH2, C( O) or NR11; and D is a group represented by the following general formula (4) or (6). In the formula (6), Q represents a single bond, S, O or NR12; and Y is a group represented by the following general formula (7). -(CR18R19)m3- Or -(CR20R21)m4-z-(CR22R23)m5 (7) z represents an optionally substituted monocyclic or polycyclic aromatic ring. In the formula (6), B represents NR25R26. In the above formulae, R1 to R26 each represents hydrogen, alkyl, alkenyl or alkynyl. |
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Namely, amine compounds represented by the following general formula (1): In a typical case, A1 and A2 represent each an optionally substituted monocyclic or polycyclic aromatic heterocycle; W represents cyclic C3-10 alkylene, an optionally substituted monocyclic or polycyclic aromatic heterocycle, a monocyclic or polycyclic aromatic ring or a partly saturated polycyclic aromatic ring; X represents O, CH2, C( O) or NR11; and D is a group represented by the following general formula (4) or (6). In the formula (6), Q represents a single bond, S, O or NR12; and Y is a group represented by the following general formula (7). -(CR18R19)m3- Or -(CR20R21)m4-z-(CR22R23)m5 (7) z represents an optionally substituted monocyclic or polycyclic aromatic ring. In the formula (6), B represents NR25R26. In the above formulae, R1 to R26 each represents hydrogen, alkyl, alkenyl or alkynyl.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2011</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110224&DB=EPODOC&CC=US&NR=2011046113A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20110224&DB=EPODOC&CC=US&NR=2011046113A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YAMAZAKI TORU</creatorcontrib><creatorcontrib>MATSUI RYO</creatorcontrib><creatorcontrib>SUZUKI SHIGERU</creatorcontrib><creatorcontrib>KIKUMOTO SHIGEYUKI</creatorcontrib><creatorcontrib>YANAKA MIKIRO</creatorcontrib><creatorcontrib>TAKEMURA YOSHIYUKI</creatorcontrib><creatorcontrib>SAITOU ATSUSHI</creatorcontrib><creatorcontrib>TAKAHASHI HARUKA</creatorcontrib><creatorcontrib>HIROSE KUNITAKA</creatorcontrib><creatorcontrib>KUMAKURA SEI</creatorcontrib><creatorcontrib>ONO MASAHIRO</creatorcontrib><title>AMINE COMPOUND AND USE THEREOF</title><description>It is intended to provide novel amine compounds which are efficacious against diseases such as infection with HIV virus, rheumatism and cancer metastasis. Namely, amine compounds represented by the following general formula (1): In a typical case, A1 and A2 represent each an optionally substituted monocyclic or polycyclic aromatic heterocycle; W represents cyclic C3-10 alkylene, an optionally substituted monocyclic or polycyclic aromatic heterocycle, a monocyclic or polycyclic aromatic ring or a partly saturated polycyclic aromatic ring; X represents O, CH2, C( O) or NR11; and D is a group represented by the following general formula (4) or (6). In the formula (6), Q represents a single bond, S, O or NR12; and Y is a group represented by the following general formula (7). -(CR18R19)m3- Or -(CR20R21)m4-z-(CR22R23)m5 (7) z represents an optionally substituted monocyclic or polycyclic aromatic ring. In the formula (6), B represents NR25R26. In the above formulae, R1 to R26 each represents hydrogen, alkyl, alkenyl or alkynyl.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2011</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJBz9PX0c1Vw9vcN8A_1c1FwBOLQYFeFEA_XIFd_Nx4G1rTEnOJUXijNzaDs5hri7KGbWpAfn1pckJicmpdaEh8abGRgaGhgYmZoaOxoaEycKgAgOCH7</recordid><startdate>20110224</startdate><enddate>20110224</enddate><creator>YAMAZAKI TORU</creator><creator>MATSUI RYO</creator><creator>SUZUKI SHIGERU</creator><creator>KIKUMOTO SHIGEYUKI</creator><creator>YANAKA MIKIRO</creator><creator>TAKEMURA YOSHIYUKI</creator><creator>SAITOU ATSUSHI</creator><creator>TAKAHASHI HARUKA</creator><creator>HIROSE KUNITAKA</creator><creator>KUMAKURA SEI</creator><creator>ONO MASAHIRO</creator><scope>EVB</scope></search><sort><creationdate>20110224</creationdate><title>AMINE COMPOUND AND USE THEREOF</title><author>YAMAZAKI TORU ; MATSUI RYO ; SUZUKI SHIGERU ; KIKUMOTO SHIGEYUKI ; YANAKA MIKIRO ; TAKEMURA YOSHIYUKI ; SAITOU ATSUSHI ; TAKAHASHI HARUKA ; HIROSE KUNITAKA ; KUMAKURA SEI ; ONO MASAHIRO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2011046113A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2011</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>YAMAZAKI TORU</creatorcontrib><creatorcontrib>MATSUI RYO</creatorcontrib><creatorcontrib>SUZUKI SHIGERU</creatorcontrib><creatorcontrib>KIKUMOTO SHIGEYUKI</creatorcontrib><creatorcontrib>YANAKA MIKIRO</creatorcontrib><creatorcontrib>TAKEMURA YOSHIYUKI</creatorcontrib><creatorcontrib>SAITOU ATSUSHI</creatorcontrib><creatorcontrib>TAKAHASHI HARUKA</creatorcontrib><creatorcontrib>HIROSE KUNITAKA</creatorcontrib><creatorcontrib>KUMAKURA SEI</creatorcontrib><creatorcontrib>ONO MASAHIRO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YAMAZAKI TORU</au><au>MATSUI RYO</au><au>SUZUKI SHIGERU</au><au>KIKUMOTO SHIGEYUKI</au><au>YANAKA MIKIRO</au><au>TAKEMURA YOSHIYUKI</au><au>SAITOU ATSUSHI</au><au>TAKAHASHI HARUKA</au><au>HIROSE KUNITAKA</au><au>KUMAKURA SEI</au><au>ONO MASAHIRO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>AMINE COMPOUND AND USE THEREOF</title><date>2011-02-24</date><risdate>2011</risdate><abstract>It is intended to provide novel amine compounds which are efficacious against diseases such as infection with HIV virus, rheumatism and cancer metastasis. Namely, amine compounds represented by the following general formula (1): In a typical case, A1 and A2 represent each an optionally substituted monocyclic or polycyclic aromatic heterocycle; W represents cyclic C3-10 alkylene, an optionally substituted monocyclic or polycyclic aromatic heterocycle, a monocyclic or polycyclic aromatic ring or a partly saturated polycyclic aromatic ring; X represents O, CH2, C( O) or NR11; and D is a group represented by the following general formula (4) or (6). In the formula (6), Q represents a single bond, S, O or NR12; and Y is a group represented by the following general formula (7). -(CR18R19)m3- Or -(CR20R21)m4-z-(CR22R23)m5 (7) z represents an optionally substituted monocyclic or polycyclic aromatic ring. In the formula (6), B represents NR25R26. In the above formulae, R1 to R26 each represents hydrogen, alkyl, alkenyl or alkynyl.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AMINE COMPOUND AND USE THEREOF |
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