PROCESS FOR MAKING SUBSTITUTED 2-AMINO-THIAZOLONES

The present invention relates to methods of making compounds that inhibit 11-hydroxysteroid dehydrogenase type 1 enzyme (11-HSD1). One method comprises (a) contacting a compound of formula (II) sequentially with a chiral base in the presence of an amine, and an alkylating agent R3-LG, (b) contacting...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	FRIZZLE MATTHEW J, MONIZ GEORGE A, FAUL MARGARET, LARROW JAY, BERNARD CHARLES, NANI ROGER, MARTINELLI MICHAEL
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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