HCV NS3 Protease Inhibitors

The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.

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Hauptverfasser: SUMMA VINCENZO, DI FRANCESCO MARIA EMILIA, MCINTYRE CHARLES A, BUTCHER JOHN W, FERRARA MARCO, HOLLOWAY M. KATHARINE, GILBERT KEVIN F, HARPER STEVEN, MCCAULEY JOHN A, PETROCCHI ALESSIA, RUDD MICHAEL T, LIVERTON NIGEL J, POMPEI MARCO, ROMANO JOSEPH J
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creator SUMMA VINCENZO
DI FRANCESCO MARIA EMILIA
MCINTYRE CHARLES A
BUTCHER JOHN W
FERRARA MARCO
HOLLOWAY M. KATHARINE
GILBERT KEVIN F
HARPER STEVEN
MCCAULEY JOHN A
PETROCCHI ALESSIA
RUDD MICHAEL T
LIVERTON NIGEL J
POMPEI MARCO
ROMANO JOSEPH J
description The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.
format Patent
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title HCV NS3 Protease Inhibitors
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