BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS

The present invention provides a compound of formula (I) wherein X is a structure of the following formula (i), (ii) (iii), or iv G is O, or S; U is -(CR3R4)n-; W is CH2NHC(=G)R1, CH2NH-het, CH2-G-het, CH2het, C(-O)NHR2; and Y1, Y2 and Y3 are independently CH, or CF. The compounds of the present inv...

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Hauptverfasser: JOSYULA VARA PRASAD VENKATA NAGENDRA, RENSLO ADAM ROBERT, GORDEEV MIKHAIL FEDOROVICH, GAO HONGWU, LUEHR GARY WAYNE
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creator JOSYULA VARA PRASAD VENKATA NAGENDRA
RENSLO ADAM ROBERT
GORDEEV MIKHAIL FEDOROVICH
GAO HONGWU
LUEHR GARY WAYNE
description The present invention provides a compound of formula (I) wherein X is a structure of the following formula (i), (ii) (iii), or iv G is O, or S; U is -(CR3R4)n-; W is CH2NHC(=G)R1, CH2NH-het, CH2-G-het, CH2het, C(-O)NHR2; and Y1, Y2 and Y3 are independently CH, or CF. The compounds of the present invention are useful as antibacterial agents.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title BENZOXAZINONE AND BENZOXAZEPINONE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS
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