DNA encoding chimeric toxin peptide fusion proteins and vectors and mammalian cells for recombinant expression
Disclosed is a composition of matter comprising an OSK1 peptide analog, and in some embodiments, a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises the composition and a pharmaceutically acceptable carrier. Also disclosed are DNAs encoding the inventive composition of...
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| creator | MCGIVERN JOSEPH G WALKER KENNETH W KHARE TARUNA ARORA ADLER BEVERLY S MIRANDA LESLIE P HU SHAW-FEN SYLVIA MARTIN FRANCIS H NGUYEN HUNG Q GEGG, JR. COLIN V SULLIVAN JOHN K |
| description | Disclosed is a composition of matter comprising an OSK1 peptide analog, and in some embodiments, a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises the composition and a pharmaceutically acceptable carrier. Also disclosed are DNAs encoding the inventive composition of matter, an expression vector comprising the DNA, and host cells comprising the expression vector. Methods of treating an autoimmune disorder and of preventing or mitigating a relapse of a symptom of multiple sclerosis are also disclosed. |
| format | Patent |
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COLIN V ; SULLIVAN JOHN K</creator><creatorcontrib>MCGIVERN JOSEPH G ; WALKER KENNETH W ; KHARE TARUNA ARORA ; ADLER BEVERLY S ; MIRANDA LESLIE P ; HU SHAW-FEN SYLVIA ; MARTIN FRANCIS H ; NGUYEN HUNG Q ; GEGG, JR. COLIN V ; SULLIVAN JOHN K</creatorcontrib><description>Disclosed is a composition of matter comprising an OSK1 peptide analog, and in some embodiments, a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises the composition and a pharmaceutically acceptable carrier. Also disclosed are DNAs encoding the inventive composition of matter, an expression vector comprising the DNA, and host cells comprising the expression vector. Methods of treating an autoimmune disorder and of preventing or mitigating a relapse of a symptom of multiple sclerosis are also disclosed.</description><language>eng</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; SUGARS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091203&DB=EPODOC&CC=US&NR=2009299044A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20091203&DB=EPODOC&CC=US&NR=2009299044A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MCGIVERN JOSEPH G</creatorcontrib><creatorcontrib>WALKER KENNETH W</creatorcontrib><creatorcontrib>KHARE TARUNA ARORA</creatorcontrib><creatorcontrib>ADLER BEVERLY S</creatorcontrib><creatorcontrib>MIRANDA LESLIE P</creatorcontrib><creatorcontrib>HU SHAW-FEN SYLVIA</creatorcontrib><creatorcontrib>MARTIN FRANCIS H</creatorcontrib><creatorcontrib>NGUYEN HUNG Q</creatorcontrib><creatorcontrib>GEGG, JR. 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Methods of treating an autoimmune disorder and of preventing or mitigating a relapse of a symptom of multiple sclerosis are also disclosed.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLsKwkAQRdNYiPoPA9ZCjDYpgw-sbNQ6rJsbHdidWXZXyeer6AdY3XPgcMeFbI8NQax2LDeyd_aIbCnrwEIBIXMH6h-J9a1RM1gSGenoCZs1ftkb741jI2ThXKJeI0VY9VcWI5kwhIj0-ZgWo964hNlvJ8V8vztvDgsEbZGCsRDk9nKqyrKu6rpcr5vl6r_qBdiIQ-8</recordid><startdate>20091203</startdate><enddate>20091203</enddate><creator>MCGIVERN JOSEPH G</creator><creator>WALKER KENNETH W</creator><creator>KHARE TARUNA ARORA</creator><creator>ADLER BEVERLY S</creator><creator>MIRANDA LESLIE P</creator><creator>HU SHAW-FEN SYLVIA</creator><creator>MARTIN FRANCIS H</creator><creator>NGUYEN HUNG Q</creator><creator>GEGG, JR. 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COLIN V</creatorcontrib><creatorcontrib>SULLIVAN JOHN K</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MCGIVERN JOSEPH G</au><au>WALKER KENNETH W</au><au>KHARE TARUNA ARORA</au><au>ADLER BEVERLY S</au><au>MIRANDA LESLIE P</au><au>HU SHAW-FEN SYLVIA</au><au>MARTIN FRANCIS H</au><au>NGUYEN HUNG Q</au><au>GEGG, JR. COLIN V</au><au>SULLIVAN JOHN K</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DNA encoding chimeric toxin peptide fusion proteins and vectors and mammalian cells for recombinant expression</title><date>2009-12-03</date><risdate>2009</risdate><abstract>Disclosed is a composition of matter comprising an OSK1 peptide analog, and in some embodiments, a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises the composition and a pharmaceutically acceptable carrier. Also disclosed are DNAs encoding the inventive composition of matter, an expression vector comprising the DNA, and host cells comprising the expression vector. Methods of treating an autoimmune disorder and of preventing or mitigating a relapse of a symptom of multiple sclerosis are also disclosed.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS |
| title | DNA encoding chimeric toxin peptide fusion proteins and vectors and mammalian cells for recombinant expression |
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