Thiazole compounds and methods of use

The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.

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Hauptverfasser: WANG XIANGHONG, HUANG XIN, LEE MATTHEW R, WOHLHIETER GEORGE E, WEILER KURT E, YUAN CHESTER CHENGUANG, RIDER JAMES T, BOURBEAU MATTHEW P, HAN NIANHE, ZENG QINGPING, VISWANADHAN VELLARKAD N, YAO GUOMIN, FOTSCH CHRISTOPHER H, LI AIWEN, ALLEN JOHN G, DOMINGUEZ CELIA, LIU QINGYIAN, TASKER ANDREW S, TADESSE SEIFU, HONG FANG-TSAO
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creator WANG XIANGHONG
HUANG XIN
LEE MATTHEW R
WOHLHIETER GEORGE E
WEILER KURT E
YUAN CHESTER CHENGUANG
RIDER JAMES T
BOURBEAU MATTHEW P
HAN NIANHE
ZENG QINGPING
VISWANADHAN VELLARKAD N
YAO GUOMIN
FOTSCH CHRISTOPHER H
LI AIWEN
ALLEN JOHN G
DOMINGUEZ CELIA
LIU QINGYIAN
TASKER ANDREW S
TADESSE SEIFU
HONG FANG-TSAO
description The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Thiazole compounds and methods of use
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