Thiazole compounds and methods of use

The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.

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Bibliographische Detailangaben
Hauptverfasser: WANG XIANGHONG, HUANG XIN, LEE MATTHEW R, WOHLHIETER GEORGE E, WEILER KURT E, YUAN CHESTER CHENGUANG, RIDER JAMES T, BOURBEAU MATTHEW P, HAN NIANHE, ZENG QINGPING, VISWANADHAN VELLARKAD N, YAO GUOMIN, FOTSCH CHRISTOPHER H, LI AIWEN, ALLEN JOHN G, DOMINGUEZ CELIA, LIU QINGYIAN, TASKER ANDREW S, TADESSE SEIFU, HONG FANG-TSAO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to methods of using thiazole compounds of Formula I and Formula II and compositions thereof for treating diseases mediated by protein kinase B (PKB) such as cancer and other proliferative disorders where the variables have the definitions provided herein.