A COUPLING DEVICE ENABLED BY MECHANICAL CONTINUITY OF CELLULAR SCAFFOLDING ACROSS TISSUE BOUNDARIES
A device and method for achieving load-bearing living-tissue-to-living-tissue coupling comprises a myriad of fine fibers extending directly from within the substance of one tissue to within the substance of the other tissue. Fibers are similar in cross-sectional area to, or smaller than, host tissue...
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| creator | MELVIN DAVID BOYD BYRNE MARK T MELVIN ALAN J |
| description | A device and method for achieving load-bearing living-tissue-to-living-tissue coupling comprises a myriad of fine fibers extending directly from within the substance of one tissue to within the substance of the other tissue. Fibers are similar in cross-sectional area to, or smaller than, host tissue cells. This enables fibers to provide a scaffolding into which proliferating cells of each tissue may grow to form a collagenous matrix enveloping individual fibers and transferring mechanical loads between each tissue's extracellular matrix and the fibers. Also taught are devices and methods (1) for delivering bundles of independent fibers into soft or hard tissue, (2) for transiently reducing tissue drag during insertion, (3) for temporarily stabilizing position during tissue ingrowth, and (4) for spatial distribution of fiber bending stress in the event of a hard tissue. |
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Also taught are devices and methods (1) for delivering bundles of independent fibers into soft or hard tissue, (2) for transiently reducing tissue drag during insertion, (3) for temporarily stabilizing position during tissue ingrowth, and (4) for spatial distribution of fiber bending stress in the event of a hard tissue.</description><language>eng</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DIAGNOSIS ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; IDENTIFICATION ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; SURGERY</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090827&DB=EPODOC&CC=US&NR=2009216252A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090827&DB=EPODOC&CC=US&NR=2009216252A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MELVIN DAVID BOYD</creatorcontrib><creatorcontrib>BYRNE MARK T</creatorcontrib><creatorcontrib>MELVIN ALAN J</creatorcontrib><title>A COUPLING DEVICE ENABLED BY MECHANICAL CONTINUITY OF CELLULAR SCAFFOLDING ACROSS TISSUE BOUNDARIES</title><description>A device and method for achieving load-bearing living-tissue-to-living-tissue coupling comprises a myriad of fine fibers extending directly from within the substance of one tissue to within the substance of the other tissue. 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| subjects | CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DIAGNOSIS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE IDENTIFICATION MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL SURGERY |
| title | A COUPLING DEVICE ENABLED BY MECHANICAL CONTINUITY OF CELLULAR SCAFFOLDING ACROSS TISSUE BOUNDARIES |
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