Pyrimidinones as Casein Kinase II (CK2) Modulators

A compound having Formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R1 and R2 are defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.

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Hauptverfasser: KIM MOON HWAN, ARCALAS ARLYN, KEARNEY PATRICK, KENNEDY ABIGAIL R, CHAN WAI KI VICKEY, MANALO JEAN-CLAIRE LIMUN, ANAND NEEL KUMAR, ZHOU PEIWEN, KOLTUN ELENA S, BUSSENIUS JOERG, DU HONGWANG, TSANG TSZE H, BLAZEY CHARLES M, IBRAHIM MOHAMED ABDULKADER, TSUHAKO AMY LEW, RICE KENNETH D, PETO CSABA J, EPSHTEYN SERGEY
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creator KIM MOON HWAN
ARCALAS ARLYN
KEARNEY PATRICK
KENNEDY ABIGAIL R
CHAN WAI KI VICKEY
MANALO JEAN-CLAIRE LIMUN
ANAND NEEL KUMAR
ZHOU PEIWEN
KOLTUN ELENA S
BUSSENIUS JOERG
DU HONGWANG
TSANG TSZE H
BLAZEY CHARLES M
IBRAHIM MOHAMED ABDULKADER
TSUHAKO AMY LEW
RICE KENNETH D
PETO CSABA J
EPSHTEYN SERGEY
description A compound having Formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R1 and R2 are defined in the specification; pharmaceutical compositions thereof; and methods of use thereof.
format Patent
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Pyrimidinones as Casein Kinase II (CK2) Modulators
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