MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION
The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection...
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| creator | JIANG YUTONG JOSEY JOHN A BLATT LAWRENCE M ANDREWS STEVEN W KENNEDY APRIL L CONDROSKI KEVIN R MADDURU MACHENDER R WOODARD LAURA DOHERTY GEORGE A WOODARD BENJAMIN T WENGLOWSKY STEVEN M STENGEL PETER J |
| description | The embodiments provide compounds of the general formulas I-XIX, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition. |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | MACROCYCLIC COMPOUNDS AS INHIBITORS OF VIRAL REPLICATION |
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