RAPID GENERATION OF T CELL-INDEPENDENT ANTIBODY RESPONSES TO T CELL-DEPENDENT ANTIGENS

The present invention comprises the use of follicular dendritic cells (FDCs) or FDC-like cells to generate FDC-dependent, but T cell-independent, B cell responses to T cell-dependent antigens, with antigen-specific and polyclonal antibody production in ~48 h. In another embodiment, a germinal center...

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Hauptverfasser: SZAKAL ANDRAS K, TEW JOHN G, WITTMAN VAUGHAN, DRAKE, III DONALD R, EL SHIKH MOHEY ELDIN MOUSTAFA, EATRIDES JENNIFER, EL SAYED RANIA, WARREN WILLIAM L
Format: Patent
Sprache:eng
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