Phenylaminopropanol Derivatives and Methods of Their Use
The present invention is directed to phenylaminopropanol derivatives of formula I: or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia...
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| creator | TRYBULSKI EUGENE JOHN ZHANG PUWEN SABATUCCI JOSEPH PETER VU AN THIEN YE FEI MARELLA MICHAEL ANTHONY MAHANEY PAIGE ERIN TEREFENKO EUGENE ANTHONY KIM CALLAIN YOUNGHEE MCCOMAS CASEY CAMERON COGHLAN RICHARD DALE HEFFERNAN GAVIN DAVID COHN STEPHEN TODD |
| description | The present invention is directed to phenylaminopropanol derivatives of formula I: or a pharmaceutically acceptable salt thereof, compositions containing these derivatives, and methods of their use for the prevention and treatment of conditions ameliorated by monoamine reuptake including, inter alia, vasomotor symptoms (VMS), sexual dysfunction, gastrointestinal and genitourinary disorders, chronic fatigue syndrome, fibromylagia syndrome, nervous system disorders, and combinations thereof, particularly those conditions selected from the group consisting of major depressive disorder, vasomotor symptoms, stress and urge urinary incontinence, fibromyalgia, pain, diabetic neuropathy, and combinations thereof. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Phenylaminopropanol Derivatives and Methods of Their Use |
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