Conjugates with Anti-Inflammatory Activity

Compounds represented by Formula I: wherein M represents a macrolide subunit of the substructure VIII: L represents the chain of the substructure IX or XIII: -X1-(CH2)m-Q-(CH2)n-X2- IX -X1-(CH2)m-V-(CH2)p-Q-(CH2)n-X2- XIII and Z represents a steroid or nonsteroidal subunit derived from steroid or no...

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Hauptverfasser:	POLJAK VISNJA, SIJAN GORDANA, SELMANI SELVIRA, MARKOVIC STRIBOR, TOMASKOVIC LINDA, MERCEP MLADEN, MESIC MILAN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS
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creator	POLJAK VISNJA SIJAN GORDANA SELMANI SELVIRA MARKOVIC STRIBOR TOMASKOVIC LINDA MERCEP MLADEN MESIC MILAN
description	Compounds represented by Formula I: wherein M represents a macrolide subunit of the substructure VIII: L represents the chain of the substructure IX or XIII: -X1-(CH2)m-Q-(CH2)n-X2- IX -X1-(CH2)m-V-(CH2)p-Q-(CH2)n-X2- XIII and Z represents a steroid or nonsteroidal subunit derived from steroid or nonsteroidal (NSAID) drugs with anti-inflammatory activity are disclosed. Pharmaceutically acceptable salts and solvates of such compounds, processes and intermediates for their preparation, as well as to the improved therapeutic action and the use in the treatment of inflammatory diseases and conditions in humans and animals are also disclosed.
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Pharmaceutically acceptable salts and solvates of such compounds, processes and intermediates for their preparation, as well as to the improved therapeutic action and the use in the treatment of inflammatory diseases and conditions in humans and animals are also disclosed.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; STEROIDS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090219&DB=EPODOC&CC=US&NR=2009048221A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090219&DB=EPODOC&CC=US&NR=2009048221A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>POLJAK VISNJA</creatorcontrib><creatorcontrib>SIJAN GORDANA</creatorcontrib><creatorcontrib>SELMANI SELVIRA</creatorcontrib><creatorcontrib>MARKOVIC STRIBOR</creatorcontrib><creatorcontrib>TOMASKOVIC LINDA</creatorcontrib><creatorcontrib>MERCEP MLADEN</creatorcontrib><creatorcontrib>MESIC MILAN</creatorcontrib><title>Conjugates with Anti-Inflammatory Activity</title><description>Compounds represented by Formula I: wherein M represents a macrolide subunit of the substructure VIII: L represents the chain of the substructure IX or XIII: -X1-(CH2)m-Q-(CH2)n-X2- IX -X1-(CH2)m-V-(CH2)p-Q-(CH2)n-X2- XIII and Z represents a steroid or nonsteroidal subunit derived from steroid or nonsteroidal (NSAID) drugs with anti-inflammatory activity are disclosed. Pharmaceutically acceptable salts and solvates of such compounds, processes and intermediates for their preparation, as well as to the improved therapeutic action and the use in the treatment of inflammatory diseases and conditions in humans and animals are also disclosed.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNByzs_LKk1PLEktVijPLMlQcMwrydT1zEvLSczNTSzJL6pUcEwuySzLLKnkYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXxocFGBgaWBiYWRkaGjobGxKkCAOhBKiU</recordid><startdate>20090219</startdate><enddate>20090219</enddate><creator>POLJAK VISNJA</creator><creator>SIJAN GORDANA</creator><creator>SELMANI SELVIRA</creator><creator>MARKOVIC STRIBOR</creator><creator>TOMASKOVIC LINDA</creator><creator>MERCEP MLADEN</creator><creator>MESIC MILAN</creator><scope>EVB</scope></search><sort><creationdate>20090219</creationdate><title>Conjugates with Anti-Inflammatory Activity</title><author>POLJAK VISNJA ; SIJAN GORDANA ; SELMANI SELVIRA ; MARKOVIC STRIBOR ; TOMASKOVIC LINDA ; MERCEP MLADEN ; MESIC MILAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2009048221A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2009</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>POLJAK VISNJA</creatorcontrib><creatorcontrib>SIJAN GORDANA</creatorcontrib><creatorcontrib>SELMANI SELVIRA</creatorcontrib><creatorcontrib>MARKOVIC STRIBOR</creatorcontrib><creatorcontrib>TOMASKOVIC LINDA</creatorcontrib><creatorcontrib>MERCEP MLADEN</creatorcontrib><creatorcontrib>MESIC MILAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>POLJAK VISNJA</au><au>SIJAN GORDANA</au><au>SELMANI SELVIRA</au><au>MARKOVIC STRIBOR</au><au>TOMASKOVIC LINDA</au><au>MERCEP MLADEN</au><au>MESIC MILAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Conjugates with Anti-Inflammatory Activity</title><date>2009-02-19</date><risdate>2009</risdate><abstract>Compounds represented by Formula I: wherein M represents a macrolide subunit of the substructure VIII: L represents the chain of the substructure IX or XIII: -X1-(CH2)m-Q-(CH2)n-X2- IX -X1-(CH2)m-V-(CH2)p-Q-(CH2)n-X2- XIII and Z represents a steroid or nonsteroidal subunit derived from steroid or nonsteroidal (NSAID) drugs with anti-inflammatory activity are disclosed. Pharmaceutically acceptable salts and solvates of such compounds, processes and intermediates for their preparation, as well as to the improved therapeutic action and the use in the treatment of inflammatory diseases and conditions in humans and animals are also disclosed.</abstract><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS
title	Conjugates with Anti-Inflammatory Activity
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