Preparation of Soluble and Colloidal Molecularly Imprinted Polymers by Living Polymerization
The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | TURNER ANTHONY PETER FRANCIS GUERRIERO ANTONIO RICARDO LEONARDO KARIM KHALKU PILETSKY SERGEY ANATOLIYOVICH PILETSKA OLENA VOLODIMIRIVNA CHIANELLA IVA |
| description | The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo. As a further aspect of the present invention, polymers synthesized as described above can be used as drugs in pharmacology and medicine, as receptor-specific ligands in analytical chemistry (sensors, assays), and for separations in the biotechnology, pharmaceutical and food industries. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2008311072A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2008311072A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2008311072A13</originalsourceid><addsrcrecordid>eNqNjLsKwkAQANNYiPoPC9ZCHoW2ISgKCoFoJ4RNbiMLm9vjLhHi1wuivdXAMMw8upeeHHocWC1oB5XK2AgBWgOFiigbFLioUDsKepng1DvPdiADpcrUkw_QTHDmJ9vHT_HrM1xGsw4l0OrLRbQ-7K_FcUNOawoOW7I01LcqjeNdliTxNs2T7L_qDcPCPRc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Preparation of Soluble and Colloidal Molecularly Imprinted Polymers by Living Polymerization</title><source>esp@cenet</source><creator>TURNER ANTHONY PETER FRANCIS ; GUERRIERO ANTONIO RICARDO LEONARDO ; KARIM KHALKU ; PILETSKY SERGEY ANATOLIYOVICH ; PILETSKA OLENA VOLODIMIRIVNA ; CHIANELLA IVA</creator><creatorcontrib>TURNER ANTHONY PETER FRANCIS ; GUERRIERO ANTONIO RICARDO LEONARDO ; KARIM KHALKU ; PILETSKY SERGEY ANATOLIYOVICH ; PILETSKA OLENA VOLODIMIRIVNA ; CHIANELLA IVA</creatorcontrib><description>The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo. As a further aspect of the present invention, polymers synthesized as described above can be used as drugs in pharmacology and medicine, as receptor-specific ligands in analytical chemistry (sensors, assays), and for separations in the biotechnology, pharmaceutical and food industries.</description><language>eng</language><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY ; CHEMISTRY ; COMPOSITIONS BASED THEREON ; HUMAN NECESSITIES ; HYGIENE ; MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC MACROMOLECULAR COMPOUNDS ; PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; THEIR PREPARATION OR CHEMICAL WORKING-UP ; THEIR RELEVANT APPARATUS ; TRANSPORTING</subject><creationdate>2008</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20081218&DB=EPODOC&CC=US&NR=2008311072A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20081218&DB=EPODOC&CC=US&NR=2008311072A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TURNER ANTHONY PETER FRANCIS</creatorcontrib><creatorcontrib>GUERRIERO ANTONIO RICARDO LEONARDO</creatorcontrib><creatorcontrib>KARIM KHALKU</creatorcontrib><creatorcontrib>PILETSKY SERGEY ANATOLIYOVICH</creatorcontrib><creatorcontrib>PILETSKA OLENA VOLODIMIRIVNA</creatorcontrib><creatorcontrib>CHIANELLA IVA</creatorcontrib><title>Preparation of Soluble and Colloidal Molecularly Imprinted Polymers by Living Polymerization</title><description>The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo. As a further aspect of the present invention, polymers synthesized as described above can be used as drugs in pharmacology and medicine, as receptor-specific ligands in analytical chemistry (sensors, assays), and for separations in the biotechnology, pharmaceutical and food industries.</description><subject>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC MACROMOLECULAR COMPOUNDS</subject><subject>PERFORMING OPERATIONS</subject><subject>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>THEIR PREPARATION OR CHEMICAL WORKING-UP</subject><subject>THEIR RELEVANT APPARATUS</subject><subject>TRANSPORTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2008</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLsKwkAQANNYiPoPC9ZCHoW2ISgKCoFoJ4RNbiMLm9vjLhHi1wuivdXAMMw8upeeHHocWC1oB5XK2AgBWgOFiigbFLioUDsKepng1DvPdiADpcrUkw_QTHDmJ9vHT_HrM1xGsw4l0OrLRbQ-7K_FcUNOawoOW7I01LcqjeNdliTxNs2T7L_qDcPCPRc</recordid><startdate>20081218</startdate><enddate>20081218</enddate><creator>TURNER ANTHONY PETER FRANCIS</creator><creator>GUERRIERO ANTONIO RICARDO LEONARDO</creator><creator>KARIM KHALKU</creator><creator>PILETSKY SERGEY ANATOLIYOVICH</creator><creator>PILETSKA OLENA VOLODIMIRIVNA</creator><creator>CHIANELLA IVA</creator><scope>EVB</scope></search><sort><creationdate>20081218</creationdate><title>Preparation of Soluble and Colloidal Molecularly Imprinted Polymers by Living Polymerization</title><author>TURNER ANTHONY PETER FRANCIS ; GUERRIERO ANTONIO RICARDO LEONARDO ; KARIM KHALKU ; PILETSKY SERGEY ANATOLIYOVICH ; PILETSKA OLENA VOLODIMIRIVNA ; CHIANELLA IVA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2008311072A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2008</creationdate><topic>CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS BASED THEREON</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>PERFORMING OPERATIONS</topic><topic>PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><topic>THEIR RELEVANT APPARATUS</topic><topic>TRANSPORTING</topic><toplevel>online_resources</toplevel><creatorcontrib>TURNER ANTHONY PETER FRANCIS</creatorcontrib><creatorcontrib>GUERRIERO ANTONIO RICARDO LEONARDO</creatorcontrib><creatorcontrib>KARIM KHALKU</creatorcontrib><creatorcontrib>PILETSKY SERGEY ANATOLIYOVICH</creatorcontrib><creatorcontrib>PILETSKA OLENA VOLODIMIRIVNA</creatorcontrib><creatorcontrib>CHIANELLA IVA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TURNER ANTHONY PETER FRANCIS</au><au>GUERRIERO ANTONIO RICARDO LEONARDO</au><au>KARIM KHALKU</au><au>PILETSKY SERGEY ANATOLIYOVICH</au><au>PILETSKA OLENA VOLODIMIRIVNA</au><au>CHIANELLA IVA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Preparation of Soluble and Colloidal Molecularly Imprinted Polymers by Living Polymerization</title><date>2008-12-18</date><risdate>2008</risdate><abstract>The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo. As a further aspect of the present invention, polymers synthesized as described above can be used as drugs in pharmacology and medicine, as receptor-specific ligands in analytical chemistry (sensors, assays), and for separations in the biotechnology, pharmaceutical and food industries.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US2008311072A1 |
| source | esp@cenet |
| subjects | CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY COMPOSITIONS BASED THEREON HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVINGCARBON-TO-CARBON UNSATURATED BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP THEIR RELEVANT APPARATUS TRANSPORTING |
| title | Preparation of Soluble and Colloidal Molecularly Imprinted Polymers by Living Polymerization |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T20%3A33%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=TURNER%20ANTHONY%20PETER%20FRANCIS&rft.date=2008-12-18&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2008311072A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |