Controlled release dosage form of tacrolimus

A controlled release dosage form of tacrolimus, comprising a solid dispersion of tacrolimus, wherein a controlled release base, which is selected from the group consisting of a water-soluble macromolecule, a gum base, and a membrane forming agent and does not form the solid dispersion of tacrolimus,...

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Hauptverfasser: ISHII TAKUYA, TAKETANI YUKO, KONDO HIROMU, YOSHIHARA KEIICHI, KOJIMA HIROYUKI
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creator ISHII TAKUYA
TAKETANI YUKO
KONDO HIROMU
YOSHIHARA KEIICHI
KOJIMA HIROYUKI
description A controlled release dosage form of tacrolimus, comprising a solid dispersion of tacrolimus, wherein a controlled release base, which is selected from the group consisting of a water-soluble macromolecule, a gum base, and a membrane forming agent and does not form the solid dispersion of tacrolimus, is further contained, is disclosed. The controlled release dosage form of tacrolimus has an excellent controlled release and shows a stable blood concentration.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Controlled release dosage form of tacrolimus
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