COMPOUNDS AND THERAPEUTICAL USE THEREOF

Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

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Hauptverfasser: CAI SUI X, WILLARDSEN ADAM, ZHANG HONG, ANDERSON MARK B, SUZUKI KAZUYUKI, SIRISOMA NILANTHA S
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creator CAI SUI X
WILLARDSEN ADAM
ZHANG HONG
ANDERSON MARK B
SUZUKI KAZUYUKI
SIRISOMA NILANTHA S
description Disclosed are 4-arylamino-quinazolines and analogs thereof effective as activators of caspases and inducers of apoptosis. The compounds of this invention are useful in the treatment of a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title COMPOUNDS AND THERAPEUTICAL USE THEREOF
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