Process for Production of Azulene Derivatives and Intermediates for the Synthesis of the Same

A process for producing an azulene derivative useful as a Na+-glucose cotransporter inhibitor, which is high in yield, is simple in operation, is low in cost, is suited for environmental protection, and is advantageous industrially, the process being characterized by reducing and deprotecting at lea...

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Hauptverfasser: MIYAFUJI AKIO, SUZUKI TAKAYUKI, IMAMURA MASAKAZU, YAMASHITA YOHEI, MIYATA JUNJI, HAYASHI YASUMASA, KOBAYASHI YOSHINORI, NAKAMURA HIROFUMI, INAKOSHI MASATOSHI, KOIDE TOKUO, SUGANE TAKASHI, TOMIYAMA HIROSHI, SAKAMOTO KENICHIRO, KAWANO NORIYUKI, NODA ATSUSHI, YOKOTA MASAYUKI, OGASAWARA JUNKO
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creator MIYAFUJI AKIO
SUZUKI TAKAYUKI
IMAMURA MASAKAZU
YAMASHITA YOHEI
MIYATA JUNJI
HAYASHI YASUMASA
KOBAYASHI YOSHINORI
NAKAMURA HIROFUMI
INAKOSHI MASATOSHI
KOIDE TOKUO
SUGANE TAKASHI
TOMIYAMA HIROSHI
SAKAMOTO KENICHIRO
KAWANO NORIYUKI
NODA ATSUSHI
YOKOTA MASAYUKI
OGASAWARA JUNKO
description A process for producing an azulene derivative useful as a Na+-glucose cotransporter inhibitor, which is high in yield, is simple in operation, is low in cost, is suited for environmental protection, and is advantageous industrially, the process being characterized by reducing and deprotecting at least one compound selected from penta-acyl compounds and tetra-acyl compounds or salts thereof to obtain a C-glycoside compound; and a useful intermediate for synthesis of such an azulene derivative, obtained in the course of the above process.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Process for Production of Azulene Derivatives and Intermediates for the Synthesis of the Same
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