Substituted 3-cyanopyridines as protein kinase inhibitors
The present teachings provide compounds of formula I and their pharmaceutically acceptable salts, hydrates, and esters, wherein R1, R2, and X are as defined herein. The present teachings also provide methods of making the compounds of formula I, and methods of treating autoimmune and inflammatory di...
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| creator | WANG YANONG D COLE DEREK C WU BIQI ASSELIN MAGDA NIU CHUAN S TUMEY LAWRENCE N JOSEPH-MCCARTHY DIANE M BOSCHELLI DIANE H PRASHAD AMARNAUTH S CHEN JOAN DUSHIN RUSSELL WISSNER ALLAN |
| description | The present teachings provide compounds of formula I and their pharmaceutically acceptable salts, hydrates, and esters, wherein R1, R2, and X are as defined herein. The present teachings also provide methods of making the compounds of formula I, and methods of treating autoimmune and inflammatory diseases by administering a therapeutically effective amount of a compound or compounds of formula I to a mammal including a human. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Substituted 3-cyanopyridines as protein kinase inhibitors |
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