PYRROLIDINE DERIVATIVES AS FACTOR XA INHIBITORS

The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.

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Hauptverfasser: KING NIGEL P, WESTON HELEN E, PATEL VIPULKUMAR K, CHAN CHUEN, HAMBLIN JULIE N, SENGER STEFAN, WHITWORTH CAROLINE, KELLY HENRY A, MASON ANDREW M, SHAH GITA P, YOUNG ROBERT J, WATSON NIGEL S
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creator KING NIGEL P
WESTON HELEN E
PATEL VIPULKUMAR K
CHAN CHUEN
HAMBLIN JULIE N
SENGER STEFAN
WHITWORTH CAROLINE
KELLY HENRY A
MASON ANDREW M
SHAH GITA P
YOUNG ROBERT J
WATSON NIGEL S
description The invention relates to compounds of formula (I) processes for their preparation, pharmaceutical compositions containing them and to their use in medicine, particularly use in the amelioration of a clinical condition for which a Factor Xa inhibitor is indicated.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRROLIDINE DERIVATIVES AS FACTOR XA INHIBITORS
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