Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders

Compounds of formula (I) and their use in therapy, particularly for the treatment of a disorder mediated by CB1 receptors such as obesity: Formula (I) wherein: R1 and R2 are independently selected from aryl; and R3 is hydrogen or alkyl; or a pharmaceutically acceptable salt or prodrug thereof, where...

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Hauptverfasser:	RUSTON VICTORIA J, HARRISON KERRY, DAVIDSON JAMES E.P, SOHAL SUHKJIT, PRATT ROBERT M, DAWSON CLAIRE E, MANSELL HOWARD L
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	RUSTON VICTORIA J HARRISON KERRY DAVIDSON JAMES E.P SOHAL SUHKJIT PRATT ROBERT M DAWSON CLAIRE E MANSELL HOWARD L
description	Compounds of formula (I) and their use in therapy, particularly for the treatment of a disorder mediated by CB1 receptors such as obesity: Formula (I) wherein: R1 and R2 are independently selected from aryl; and R3 is hydrogen or alkyl; or a pharmaceutically acceptable salt or prodrug thereof, wherein at least one of R1 and R2 has a non-hydrogen substituent in the ortho-position(s) thereof relative to the point of attachment to the [-CH-0-] group.
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title	Azetidinecarboxamide derivatives and their use in the treatment of cb1 receptor mediated disorders
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