Potent LNA oligonucleotides for the inhibition of HIF-1a expression

The present disclosure relates to an LNA oligonucleotide consisting of a sequence selected from the group consisting of 5'-(Tx)GxGxcsasasgscsastscscsTxGxT-3' and 5'-(Gx)TxTxascstsgscscststscsTxTxA-3', wherein capital letters designate a beta-D-oxy-LNA nucleotide analogue, small l...

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Hauptverfasser:	HANSEN HENRIK F, RASMUSSEN FRANK W, WESTERGAARD MAJKEN, THRUE CHARLOTTE A
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
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