Process to obtain 6-O-methylerythromycin a (clarithromycin)_form II

Process to obtain 6-O-methylerythromycin a (clarithromycin)_form II

The present invention provides a process for the preparation of 6-O-methylerythromycin A Form II comprising treating 6-O-methylerythromycin A with organic acid selected form trifluoroacetic acid, para-toluene sulphonic acid, oxalic acid or acetic acid and converting it into an organic salt of 6-O-me...

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Hauptverfasser: DAVE BHAVISHA N, SONI ROHIT R, PANDEY ANAND K, DESHPANDE PANDURANG B, THORAT MAHADEO M
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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creator DAVE BHAVISHA N
SONI ROHIT R
PANDEY ANAND K
DESHPANDE PANDURANG B
THORAT MAHADEO M
description The present invention provides a process for the preparation of 6-O-methylerythromycin A Form II comprising treating 6-O-methylerythromycin A with organic acid selected form trifluoroacetic acid, para-toluene sulphonic acid, oxalic acid or acetic acid and converting it into an organic salt of 6-O-methylerythromycin A, which can be neutralized by base to give 6-O-methylerythromycin A Form II.
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subjects CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
title Process to obtain 6-O-methylerythromycin a (clarithromycin)_form II
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