Process for the preparation of naphthylmethylamine derivatives

Disclosed is a process for the preparation of a naphthylmethylamine derivative or a pharmaceutically acceptable salt thereof of Formula I wherein R1 is a lower straight or branched alkyl group and R2 is a lower straight or branched alkyl group, aryl group or araylalkyl group, the process comprising...

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Hauptverfasser: BHIRUD SHEKHAR BHASKAR, SRIDHARAN RAMASUBRAMANIAN, JANRAO RAVINDRA ASHOK, PURUSHOTHAM VANDANAPU LOKA APPALA
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creator BHIRUD SHEKHAR BHASKAR
SRIDHARAN RAMASUBRAMANIAN
JANRAO RAVINDRA ASHOK
PURUSHOTHAM VANDANAPU LOKA APPALA
description Disclosed is a process for the preparation of a naphthylmethylamine derivative or a pharmaceutically acceptable salt thereof of Formula I wherein R1 is a lower straight or branched alkyl group and R2 is a lower straight or branched alkyl group, aryl group or araylalkyl group, the process comprising reacting a N-alkyl-1-naphthylmethylamine HCl compound of Formula II: wherein R1 has the aforestated meaning, with a compound of Formula III wherein X is a halogen and R2 has the aforestated meaning in the presence of at least one base and in at least one solvent.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
title Process for the preparation of naphthylmethylamine derivatives
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