Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole

A process is disclosed for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole, which comprises reacting (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole with a borane reagent in the presence of suitable organic solvent to yield (S)-2-amino-6-propylamino-4,5,6,7-tet...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	KASPI JOSEPH, SHOOKRUN MOTY, BRAND MICHAEL, SALMAN ADA, GRIBUN IRINA, SHIFFER MEITAL, ARAD ODED
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page
container_issue
container_start_page
container_title
container_volume
creator	KASPI JOSEPH SHOOKRUN MOTY BRAND MICHAEL SALMAN ADA GRIBUN IRINA SHIFFER MEITAL ARAD ODED
description	A process is disclosed for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole, which comprises reacting (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole with a borane reagent in the presence of suitable organic solvent to yield (S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole base, which may be converted to an acid addition salt thereof. The process provided herein can be easily, conveniently and inexpensively scaled-up.
format	Patent
fullrecord	<record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2006069263A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2006069263A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2006069263A13</originalsourceid><addsrcrecordid>eNqNirEKwjAUALs4iPoPAReFPIipRhxFFEehCm4lbV9IoOaFJA726-3gBzgdx920eN4itZgSMxRZtsgidu82O_KMDFtVa5CgX84TKAiRwhhG7Qi2fMcV30PGHLX9dJEa9ANBtk4P1OO8mBjdJ1z8OCuWl_P9dAUMVGMKukWPuX5UUggl1EGq8rgp_7u-fEk5ag</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole</title><source>esp@cenet</source><creator>KASPI JOSEPH ; SHOOKRUN MOTY ; BRAND MICHAEL ; SALMAN ADA ; GRIBUN IRINA ; SHIFFER MEITAL ; ARAD ODED</creator><creatorcontrib>KASPI JOSEPH ; SHOOKRUN MOTY ; BRAND MICHAEL ; SALMAN ADA ; GRIBUN IRINA ; SHIFFER MEITAL ; ARAD ODED</creatorcontrib><description>A process is disclosed for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole, which comprises reacting (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole with a borane reagent in the presence of suitable organic solvent to yield (S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole base, which may be converted to an acid addition salt thereof. The process provided herein can be easily, conveniently and inexpensively scaled-up.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060330&DB=EPODOC&CC=US&NR=2006069263A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060330&DB=EPODOC&CC=US&NR=2006069263A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KASPI JOSEPH</creatorcontrib><creatorcontrib>SHOOKRUN MOTY</creatorcontrib><creatorcontrib>BRAND MICHAEL</creatorcontrib><creatorcontrib>SALMAN ADA</creatorcontrib><creatorcontrib>GRIBUN IRINA</creatorcontrib><creatorcontrib>SHIFFER MEITAL</creatorcontrib><creatorcontrib>ARAD ODED</creatorcontrib><title>Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole</title><description>A process is disclosed for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole, which comprises reacting (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole with a borane reagent in the presence of suitable organic solvent to yield (S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole base, which may be converted to an acid addition salt thereof. The process provided herein can be easily, conveniently and inexpensively scaled-up.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2006</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNirEKwjAUALs4iPoPAReFPIipRhxFFEehCm4lbV9IoOaFJA726-3gBzgdx920eN4itZgSMxRZtsgidu82O_KMDFtVa5CgX84TKAiRwhhG7Qi2fMcV30PGHLX9dJEa9ANBtk4P1OO8mBjdJ1z8OCuWl_P9dAUMVGMKukWPuX5UUggl1EGq8rgp_7u-fEk5ag</recordid><startdate>20060330</startdate><enddate>20060330</enddate><creator>KASPI JOSEPH</creator><creator>SHOOKRUN MOTY</creator><creator>BRAND MICHAEL</creator><creator>SALMAN ADA</creator><creator>GRIBUN IRINA</creator><creator>SHIFFER MEITAL</creator><creator>ARAD ODED</creator><scope>EVB</scope></search><sort><creationdate>20060330</creationdate><title>Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole</title><author>KASPI JOSEPH ; SHOOKRUN MOTY ; BRAND MICHAEL ; SALMAN ADA ; GRIBUN IRINA ; SHIFFER MEITAL ; ARAD ODED</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2006069263A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2006</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>KASPI JOSEPH</creatorcontrib><creatorcontrib>SHOOKRUN MOTY</creatorcontrib><creatorcontrib>BRAND MICHAEL</creatorcontrib><creatorcontrib>SALMAN ADA</creatorcontrib><creatorcontrib>GRIBUN IRINA</creatorcontrib><creatorcontrib>SHIFFER MEITAL</creatorcontrib><creatorcontrib>ARAD ODED</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KASPI JOSEPH</au><au>SHOOKRUN MOTY</au><au>BRAND MICHAEL</au><au>SALMAN ADA</au><au>GRIBUN IRINA</au><au>SHIFFER MEITAL</au><au>ARAD ODED</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole</title><date>2006-03-30</date><risdate>2006</risdate><abstract>A process is disclosed for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole, which comprises reacting (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzothiazole with a borane reagent in the presence of suitable organic solvent to yield (S)-2-amino-6-propylamino-4,5,6,7-tetrahydrobenzothiazole base, which may be converted to an acid addition salt thereof. The process provided herein can be easily, conveniently and inexpensively scaled-up.</abstract><oa>free_for_read</oa></addata></record>
fulltext	fulltext_linktorsrc
identifier
ispartof
issn
language	eng
recordid	cdi_epo_espacenet_US2006069263A1
source	esp@cenet
subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
title	Process for the reduction of (S)-2-amino-6-propionamido-4,5,6,7-tetrahydrobenzo-thiazole
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-07T22%3A45%3A58IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KASPI%20JOSEPH&rft.date=2006-03-30&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2006069263A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true