Urea derivatives
This invention relates to urea derivatives and salts thereof which is useful as an active ingredient of pharmaceutical preparations. The urea derivatives of the present invention has an excellent activity as VR1 antagonist and useful for the prophylaxis and treatment of diseases associated with VR1...
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| creator | MOGI MUNETO URBAHNS KLAUS TAJIMI MASAOMI MASUDA TSUTOMU KOKUBO TOSHIO MARUMO MAKIKO YURA TAKESHI TAKESHITA KEISUKE TSUKIMI YASUHIRO SHIROO MASAHIRO IKEGAMI YUKA MORIWAKI TOSHIYA YOSHIDA NAGAHIRO |
| description | This invention relates to urea derivatives and salts thereof which is useful as an active ingredient of pharmaceutical preparations. The urea derivatives of the present invention has an excellent activity as VR1 antagonist and useful for the prophylaxis and treatment of diseases associated with VR1 activity, in particular for the treatment of urge urinary incontinence, overactive bladder, chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, incontinence and/or inflammatory disorders. |
| format | Patent |
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The urea derivatives of the present invention has an excellent activity as VR1 antagonist and useful for the prophylaxis and treatment of diseases associated with VR1 activity, in particular for the treatment of urge urinary incontinence, overactive bladder, chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, incontinence and/or inflammatory disorders.</description><edition>7</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050714&DB=EPODOC&CC=US&NR=2005154230A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050714&DB=EPODOC&CC=US&NR=2005154230A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MOGI MUNETO</creatorcontrib><creatorcontrib>URBAHNS KLAUS</creatorcontrib><creatorcontrib>TAJIMI MASAOMI</creatorcontrib><creatorcontrib>MASUDA TSUTOMU</creatorcontrib><creatorcontrib>KOKUBO TOSHIO</creatorcontrib><creatorcontrib>MARUMO MAKIKO</creatorcontrib><creatorcontrib>YURA TAKESHI</creatorcontrib><creatorcontrib>TAKESHITA KEISUKE</creatorcontrib><creatorcontrib>TSUKIMI YASUHIRO</creatorcontrib><creatorcontrib>SHIROO MASAHIRO</creatorcontrib><creatorcontrib>IKEGAMI YUKA</creatorcontrib><creatorcontrib>MORIWAKI TOSHIYA</creatorcontrib><creatorcontrib>YOSHIDA NAGAHIRO</creatorcontrib><title>Urea derivatives</title><description>This invention relates to urea derivatives and salts thereof which is useful as an active ingredient of pharmaceutical preparations. 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The urea derivatives of the present invention has an excellent activity as VR1 antagonist and useful for the prophylaxis and treatment of diseases associated with VR1 activity, in particular for the treatment of urge urinary incontinence, overactive bladder, chronic pain, neuropathic pain, postoperative pain, rheumatoid arthritic pain, neuralgia, neuropathies, algesia, nerve injury, ischaemia, neurodegeneration, stroke, incontinence and/or inflammatory disorders.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| language | eng |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Urea derivatives |
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