Hydronopol derivatives as agonists on human ORL1 receptors
The invention relates to a group of hydronopol derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these novel hydronopol...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | JASSERAND DANIEL SCHON UWE VAN STEEN BARTHOLOMEUS J REICHE DANIA B DAVID SAMUEL PREUSCHOFF ULF MENTZEL MATTHIAS BRUCKNER REINHARD |
| description | The invention relates to a group of hydronopol derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these novel hydronopol derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which ORL1 receptors are involved. The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2005131004A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2005131004A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2005131004A13</originalsourceid><addsrcrecordid>eNrjZLDyqEwpys_LL8jPUUhJLcosSyzJLEstVkgEovT8vMzikmKF_DyFjNLcxDwF_yAfQ4Wi1OTUgpL8omIeBta0xJziVF4ozc2g7OYa4uyhm1qQH59aXJCYnJqXWhIfGmxkYGBqaGxoYGDiaGhMnCoAOQIv0A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Hydronopol derivatives as agonists on human ORL1 receptors</title><source>esp@cenet</source><creator>JASSERAND DANIEL ; SCHON UWE ; VAN STEEN BARTHOLOMEUS J ; REICHE DANIA B ; DAVID SAMUEL ; PREUSCHOFF ULF ; MENTZEL MATTHIAS ; BRUCKNER REINHARD</creator><creatorcontrib>JASSERAND DANIEL ; SCHON UWE ; VAN STEEN BARTHOLOMEUS J ; REICHE DANIA B ; DAVID SAMUEL ; PREUSCHOFF ULF ; MENTZEL MATTHIAS ; BRUCKNER REINHARD</creatorcontrib><description>The invention relates to a group of hydronopol derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these novel hydronopol derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which ORL1 receptors are involved. The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050616&DB=EPODOC&CC=US&NR=2005131004A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050616&DB=EPODOC&CC=US&NR=2005131004A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JASSERAND DANIEL</creatorcontrib><creatorcontrib>SCHON UWE</creatorcontrib><creatorcontrib>VAN STEEN BARTHOLOMEUS J</creatorcontrib><creatorcontrib>REICHE DANIA B</creatorcontrib><creatorcontrib>DAVID SAMUEL</creatorcontrib><creatorcontrib>PREUSCHOFF ULF</creatorcontrib><creatorcontrib>MENTZEL MATTHIAS</creatorcontrib><creatorcontrib>BRUCKNER REINHARD</creatorcontrib><title>Hydronopol derivatives as agonists on human ORL1 receptors</title><description>The invention relates to a group of hydronopol derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these novel hydronopol derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which ORL1 receptors are involved. The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDyqEwpys_LL8jPUUhJLcosSyzJLEstVkgEovT8vMzikmKF_DyFjNLcxDwF_yAfQ4Wi1OTUgpL8omIeBta0xJziVF4ozc2g7OYa4uyhm1qQH59aXJCYnJqXWhIfGmxkYGBqaGxoYGDiaGhMnCoAOQIv0A</recordid><startdate>20050616</startdate><enddate>20050616</enddate><creator>JASSERAND DANIEL</creator><creator>SCHON UWE</creator><creator>VAN STEEN BARTHOLOMEUS J</creator><creator>REICHE DANIA B</creator><creator>DAVID SAMUEL</creator><creator>PREUSCHOFF ULF</creator><creator>MENTZEL MATTHIAS</creator><creator>BRUCKNER REINHARD</creator><scope>EVB</scope></search><sort><creationdate>20050616</creationdate><title>Hydronopol derivatives as agonists on human ORL1 receptors</title><author>JASSERAND DANIEL ; SCHON UWE ; VAN STEEN BARTHOLOMEUS J ; REICHE DANIA B ; DAVID SAMUEL ; PREUSCHOFF ULF ; MENTZEL MATTHIAS ; BRUCKNER REINHARD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2005131004A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2005</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>JASSERAND DANIEL</creatorcontrib><creatorcontrib>SCHON UWE</creatorcontrib><creatorcontrib>VAN STEEN BARTHOLOMEUS J</creatorcontrib><creatorcontrib>REICHE DANIA B</creatorcontrib><creatorcontrib>DAVID SAMUEL</creatorcontrib><creatorcontrib>PREUSCHOFF ULF</creatorcontrib><creatorcontrib>MENTZEL MATTHIAS</creatorcontrib><creatorcontrib>BRUCKNER REINHARD</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>JASSERAND DANIEL</au><au>SCHON UWE</au><au>VAN STEEN BARTHOLOMEUS J</au><au>REICHE DANIA B</au><au>DAVID SAMUEL</au><au>PREUSCHOFF ULF</au><au>MENTZEL MATTHIAS</au><au>BRUCKNER REINHARD</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Hydronopol derivatives as agonists on human ORL1 receptors</title><date>2005-06-16</date><risdate>2005</risdate><abstract>The invention relates to a group of hydronopol derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these novel hydronopol derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which ORL1 receptors are involved. The invention relates to compounds of the general formula (1) wherein the symbols have the meanings as given in the description.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US2005131004A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Hydronopol derivatives as agonists on human ORL1 receptors |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T21%3A51%3A32IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=JASSERAND%20DANIEL&rft.date=2005-06-16&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2005131004A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |