Medical device with porous surface containing bioerodable bioactive composites and related methods
An implantable medical device includes a porous surface with a composite material located within the pores that includes a bioerodable material in combination with a bioactive agent. The composite material is adapted to erode upon exposure to the body of a patient, thus releasing the bioactive agent...
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creator | PEACOCK JAMES C.III |
description | An implantable medical device includes a porous surface with a composite material located within the pores that includes a bioerodable material in combination with a bioactive agent. The composite material is adapted to erode upon exposure to the body of a patient, thus releasing the bioactive agent into the patient, whereas the porous surface remains on the device. In one embodiment, the composite material includes micro- or nano-particles that are deposited within the pores. In a further embodiment, the porous surface is an electrolessly electrochemically deposited material. Certain tie layer and other surface modification aspects are described to enhance various aspects of the bioactive composite surface. The bioactive composite surface is of particular benefit when provided on an endolumenal stent assembly in a manner adapted to elute anti-restenosis or anti-thrombosis agents or combinations thereof. |
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The composite material is adapted to erode upon exposure to the body of a patient, thus releasing the bioactive agent into the patient, whereas the porous surface remains on the device. In one embodiment, the composite material includes micro- or nano-particles that are deposited within the pores. In a further embodiment, the porous surface is an electrolessly electrochemically deposited material. Certain tie layer and other surface modification aspects are described to enhance various aspects of the bioactive composite surface. The bioactive composite surface is of particular benefit when provided on an endolumenal stent assembly in a manner adapted to elute anti-restenosis or anti-thrombosis agents or combinations thereof.</description><edition>7</edition><language>eng</language><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS ; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; FILTERS IMPLANTABLE INTO BLOOD VESSELS ; FIRST-AID KITS ; FOMENTATION ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES ; PROSTHESES ; TREATMENT OR PROTECTION OF EYES OR EARS</subject><creationdate>2005</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050602&DB=EPODOC&CC=US&NR=2005119723A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20050602&DB=EPODOC&CC=US&NR=2005119723A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PEACOCK JAMES C.III</creatorcontrib><title>Medical device with porous surface containing bioerodable bioactive composites and related methods</title><description>An implantable medical device includes a porous surface with a composite material located within the pores that includes a bioerodable material in combination with a bioactive agent. The composite material is adapted to erode upon exposure to the body of a patient, thus releasing the bioactive agent into the patient, whereas the porous surface remains on the device. In one embodiment, the composite material includes micro- or nano-particles that are deposited within the pores. In a further embodiment, the porous surface is an electrolessly electrochemically deposited material. Certain tie layer and other surface modification aspects are described to enhance various aspects of the bioactive composite surface. The bioactive composite surface is of particular benefit when provided on an endolumenal stent assembly in a manner adapted to elute anti-restenosis or anti-thrombosis agents or combinations thereof.</description><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS</subject><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</subject><subject>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</subject><subject>FILTERS IMPLANTABLE INTO BLOOD VESSELS</subject><subject>FIRST-AID KITS</subject><subject>FOMENTATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><subject>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</subject><subject>PROSTHESES</subject><subject>TREATMENT OR PROTECTION OF EYES OR EARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2005</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjbsKwkAQRdNYiPoPA9ZCHohYiig2VmodJrsTM7DZWXYn8fdNwA-wuofDgbvMmjtZNujA0siG4MPaQZAoQ4I0xBYnZ8Qrsmf_hoaFolhsHM2MRnmcgz5IYqUE6C1EcqhkoSftxKZ1tmjRJdr8dpVtr5fn-bajIDWlMF140vr1KPN8XxTHQ1mdiuq_6gugPz-r</recordid><startdate>20050602</startdate><enddate>20050602</enddate><creator>PEACOCK JAMES C.III</creator><scope>EVB</scope></search><sort><creationdate>20050602</creationdate><title>Medical device with porous surface containing bioerodable bioactive composites and related methods</title><author>PEACOCK JAMES C.III</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2005119723A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2005</creationdate><topic>BANDAGES, DRESSINGS OR ABSORBENT PADS</topic><topic>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</topic><topic>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PROSTHESES</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>PEACOCK JAMES C.III</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PEACOCK JAMES C.III</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Medical device with porous surface containing bioerodable bioactive composites and related methods</title><date>2005-06-02</date><risdate>2005</risdate><abstract>An implantable medical device includes a porous surface with a composite material located within the pores that includes a bioerodable material in combination with a bioactive agent. The composite material is adapted to erode upon exposure to the body of a patient, thus releasing the bioactive agent into the patient, whereas the porous surface remains on the device. In one embodiment, the composite material includes micro- or nano-particles that are deposited within the pores. In a further embodiment, the porous surface is an electrolessly electrochemically deposited material. Certain tie layer and other surface modification aspects are described to enhance various aspects of the bioactive composite surface. The bioactive composite surface is of particular benefit when provided on an endolumenal stent assembly in a manner adapted to elute anti-restenosis or anti-thrombosis agents or combinations thereof.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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subjects | BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES TREATMENT OR PROTECTION OF EYES OR EARS |
title | Medical device with porous surface containing bioerodable bioactive composites and related methods |
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