Method for the preparation of tetrahydrobenzothiepines
Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of suc...
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creator | MILLER LAWRENCE M PRZYBYLA CLAIRE A LI JAMES WAGNER GRACE M CARPENTER ANDREW HETT ROBERT WEISENBURGER GERALD A BABIAK KEVIN A COLSON PIERRE-JEAN ORLOVSKI VLADISLAV POZZO MARK J HUBER CHRISTIAN H CHOU SHINE PETERSON JAMES C KOELLER KEVIN J TREMONT SAMUEL J ZHI BENXIN LAWSON JON P MAR EDUARDO K PAYMAN FARID TRIVEDI JAY S |
description | Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of such compounds; the provision of a process for the preparation of 3-bromo-2-substituted propionaldehyde compounds; and the provision of a process for the preparation of 3-thio-2-substituted propionaldehyde compounds. |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Method for the preparation of tetrahydrobenzothiepines |
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