Substituted benzopyran derivatives for the treatment of inflammation

A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' wherein X, A , A , A , A , R, R'', R and R are as described in the specification.

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Hauptverfasser: METZ SUZANNE, LUDWIG CINDY L, GRANETO MATTHEW J, ROGIER DONALD J, NAGARAJAN SRINIVASAN RAJ, KORTE DONALD E, BROWN DAVID L, TALLEY JOHN J, CARTER JEFFERY S, DEVADAS BALEKUDRU, HANAU CATHLEEN E, BERTENSHAW STEPHEN R, HARTMANN SUSAN J, OBUKOWICZ MARK G
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creator METZ SUZANNE
LUDWIG CINDY L
GRANETO MATTHEW J
ROGIER DONALD J
NAGARAJAN SRINIVASAN RAJ
KORTE DONALD E
BROWN DAVID L
TALLEY JOHN J
CARTER JEFFERY S
DEVADAS BALEKUDRU
HANAU CATHLEEN E
BERTENSHAW STEPHEN R
HARTMANN SUSAN J
OBUKOWICZ MARK G
description A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' wherein X, A , A , A , A , R, R'', R and R are as described in the specification.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Substituted benzopyran derivatives for the treatment of inflammation
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