Substituted benzopyran derivatives for the treatment of inflammation

A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' wherein X, A , A , A , A , R, R'', R and R are as described in the specification.

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Hauptverfasser: METZ SUZANNE, LUDWIG CINDY L, GRANETO MATTHEW J, ROGIER DONALD J, NAGARAJAN SRINIVASAN RAJ, KORTE DONALD E, BROWN DAVID L, TALLEY JOHN J, CARTER JEFFERY S, DEVADAS BALEKUDRU, HANAU CATHLEEN E, BERTENSHAW STEPHEN R, HARTMANN SUSAN J, OBUKOWICZ MARK G
Format: Patent
Sprache:eng
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Zusammenfassung:A class of benzopyran, derivatives is described for use in treating cyclooxygenase-2 mediated disorders. Compounds of particular interest are defined by Formula I' wherein X, A , A , A , A , R, R'', R and R are as described in the specification.