Target-specific activatable polymeric imaging agents

Target-specific activatable polymeric imaging agents

A target-specific image-enhancing agent for medical imaging comprises an extended poly(amino acid), wherein at least 90 percent of the amino acid residues are conjugated to signal-generating moieties attached to signal-controlling moieties via bonds that are cleavable by a physiological substance pr...

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Hauptverfasser: UZGIRIS EGIDIJUS EDWARD, AMARATUNGA MOHAN MARK
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator UZGIRIS EGIDIJUS EDWARD
AMARATUNGA MOHAN MARK
description A target-specific image-enhancing agent for medical imaging comprises an extended poly(amino acid), wherein at least 90 percent of the amino acid residues are conjugated to signal-generating moieties attached to signal-controlling moieties via bonds that are cleavable by a physiological substance produced by the target. The image-enhancing agent becomes activated when the bonds is cleaved by the physiological substance. The image-enhancing agent is used in detecting and/or diagnosing a disease that is characterized by an overproduction of the substance.
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HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Target-specific activatable polymeric imaging agents
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