Enteric formulations of proanthocyanidin polymer antidiarrheal compositions

Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer composition which has been isolated from...

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Hauptverfasser: CHAN JODY WAI-HAN, ROZHON EDWARD JAMES, KHANDWALA ATUL S, SABOUNI AKRAM, BALWANI GUL P, SESIN DAVID F
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creator CHAN JODY WAI-HAN
ROZHON EDWARD JAMES
KHANDWALA ATUL S
SABOUNI AKRAM
BALWANI GUL P
SESIN DAVID F
description Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer composition which has been isolated from a Croton spp. or a Calophyllum spp. In particular, the invention relates to a formulation of a proanthocyanidin polymer composition which protects the composition from the effects of stomach acid after oral administration, particularly to those formulations which are enteric coated. The invention also relates to methods of producing a directly compressible proanthocyanidin polymer composition, as well as compositions containing the directly compressible proanthocyanidin polymer composition.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Enteric formulations of proanthocyanidin polymer antidiarrheal compositions
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