Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade
This invention discloses amino acid derivatives which display inhibitory effects on the serine protease factor Xa. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, methods for the prepar...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LEONARD DANIELE MARIE BOLTON GARY LOUIS FILIPSKI KEVIN JAMES KOHRT JEFFREY THOMAS LA FRANCES |
| description | This invention discloses amino acid derivatives which display inhibitory effects on the serine protease factor Xa. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, methods for the preparation of the compounds, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2004167131A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2004167131A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2004167131A13</originalsourceid><addsrcrecordid>eNqNyj0KAjEQQOFtLES9w4C1sHFFaxFFa3-wW8Zk4gbCTMjEPb8pPIDV-4o3bR4XHsIrFMkK4sGjrYQnArIDKQNlUMqBCVKWQqikEHiUOJKrgHqAFXx_IpYgDBbVoqN5M_EYlRa_zprl6Xg7nFeUpCdNaImp9Pfrum03Zrszndmb7r_rC-t7OlU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade</title><source>esp@cenet</source><creator>LEONARD DANIELE MARIE ; BOLTON GARY LOUIS ; FILIPSKI KEVIN JAMES ; KOHRT JEFFREY THOMAS ; LA FRANCES</creator><creatorcontrib>LEONARD DANIELE MARIE ; BOLTON GARY LOUIS ; FILIPSKI KEVIN JAMES ; KOHRT JEFFREY THOMAS ; LA FRANCES</creatorcontrib><description>This invention discloses amino acid derivatives which display inhibitory effects on the serine protease factor Xa. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, methods for the preparation of the compounds, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.</description><edition>7</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040826&DB=EPODOC&CC=US&NR=2004167131A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040826&DB=EPODOC&CC=US&NR=2004167131A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEONARD DANIELE MARIE</creatorcontrib><creatorcontrib>BOLTON GARY LOUIS</creatorcontrib><creatorcontrib>FILIPSKI KEVIN JAMES</creatorcontrib><creatorcontrib>KOHRT JEFFREY THOMAS</creatorcontrib><creatorcontrib>LA FRANCES</creatorcontrib><title>Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade</title><description>This invention discloses amino acid derivatives which display inhibitory effects on the serine protease factor Xa. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, methods for the preparation of the compounds, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyj0KAjEQQOFtLES9w4C1sHFFaxFFa3-wW8Zk4gbCTMjEPb8pPIDV-4o3bR4XHsIrFMkK4sGjrYQnArIDKQNlUMqBCVKWQqikEHiUOJKrgHqAFXx_IpYgDBbVoqN5M_EYlRa_zprl6Xg7nFeUpCdNaImp9Pfrum03Zrszndmb7r_rC-t7OlU</recordid><startdate>20040826</startdate><enddate>20040826</enddate><creator>LEONARD DANIELE MARIE</creator><creator>BOLTON GARY LOUIS</creator><creator>FILIPSKI KEVIN JAMES</creator><creator>KOHRT JEFFREY THOMAS</creator><creator>LA FRANCES</creator><scope>EVB</scope></search><sort><creationdate>20040826</creationdate><title>Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade</title><author>LEONARD DANIELE MARIE ; BOLTON GARY LOUIS ; FILIPSKI KEVIN JAMES ; KOHRT JEFFREY THOMAS ; LA FRANCES</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2004167131A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2004</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>LEONARD DANIELE MARIE</creatorcontrib><creatorcontrib>BOLTON GARY LOUIS</creatorcontrib><creatorcontrib>FILIPSKI KEVIN JAMES</creatorcontrib><creatorcontrib>KOHRT JEFFREY THOMAS</creatorcontrib><creatorcontrib>LA FRANCES</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEONARD DANIELE MARIE</au><au>BOLTON GARY LOUIS</au><au>FILIPSKI KEVIN JAMES</au><au>KOHRT JEFFREY THOMAS</au><au>LA FRANCES</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade</title><date>2004-08-26</date><risdate>2004</risdate><abstract>This invention discloses amino acid derivatives which display inhibitory effects on the serine protease factor Xa. The invention also discloses pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable compositions comprising the compounds or their salts, methods for the preparation of the compounds, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_US2004167131A1 |
| source | esp@cenet |
| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-06T13%3A30%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LEONARD%20DANIELE%20MARIE&rft.date=2004-08-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2004167131A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |