Ring modified cyclic peptide analogs

A method for modifying the cyclic peptide ring system of Echinocandin-type compounds to produce new analogs having antifungal activity is provided. The inventive process comprises opening the cyclic peptide ring, cleaving the terminal ornithine unit, inserting at least one new amino acid or other sy...

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Bibliographische Detailangaben

Hauptverfasser:	TURNER WILLIAM W, JUNGHEIM LOUIS N, MAYHUGH DANIEL R, COHEN JEFFREY D, GREGORY GEORGE S, HITCHCOCK STEPHEN A, BORROMEO PETER S, SHEPHERED TIMOTHY A, HENLE STACY K
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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