Novel proteins and nucleic acids encoding same
The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide...
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| creator | JI WEIZHEN GUNTHER ERIK TCHERNEV VELIZAR T VERNET CORINE A.M BURGESS CATHERINE E CHANT JOHN S ORT TATIANA WOLENC ADAM R BERGHS CONSTANCE SHIMKETS RICHARD A GUO XIAOJIA SASHA LI LI SHENOY SURESH G STONE DAVID J EDINGER SHLOMIT R ZHONG MEI LIU XIAOHONG RASTELLI LUCA MILLET ISABELLE GANGOLLI ESHA A GORMAN LINDA PENA CAROL E.A SPYTEK KIMBERLY A FURTAK KATARZYNA ANDERSON DAVID W SMITHSON GLENNDA CASMAN STACIE J ELLERMAN KAREN MISHRA VISHNU BALLINGER ROBERT A TAUPIER RAYMOND J ZERHUSEN BRYAN D MACDOUGALL JOHN R MILLER CHARLES E PADIGARU MURALIDHARA GERLACH VALERIE PATTURAJAN MEERA BAUMGARTNER JASON C GILBERT JENNIFER A SPADERNA STEVEN K |
| description | The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2004043929A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2004043929A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2004043929A13</originalsourceid><addsrcrecordid>eNrjZNDzyy9LzVEoKMovSc3MK1ZIzEtRyCtNzknNTFZITM5MKVZIzUvOT8nMS1coTsxN5WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8aHBRgYGJgYmxpZGlo6GxsSpAgCQcytK</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Novel proteins and nucleic acids encoding same</title><source>esp@cenet</source><creator>JI WEIZHEN ; GUNTHER ERIK ; TCHERNEV VELIZAR T ; VERNET CORINE A.M ; BURGESS CATHERINE E ; CHANT JOHN S ; ORT TATIANA ; WOLENC ADAM R ; BERGHS CONSTANCE ; SHIMKETS RICHARD A ; GUO XIAOJIA SASHA ; LI LI ; SHENOY SURESH G ; STONE DAVID J ; EDINGER SHLOMIT R ; ZHONG MEI ; LIU XIAOHONG ; RASTELLI LUCA ; MILLET ISABELLE ; GANGOLLI ESHA A ; GORMAN LINDA ; PENA CAROL E.A ; SPYTEK KIMBERLY A ; FURTAK KATARZYNA ; ANDERSON DAVID W ; SMITHSON GLENNDA ; CASMAN STACIE J ; ELLERMAN KAREN ; MISHRA VISHNU ; BALLINGER ROBERT A ; TAUPIER RAYMOND J ; ZERHUSEN BRYAN D ; MACDOUGALL JOHN R ; MILLER CHARLES E ; PADIGARU MURALIDHARA ; GERLACH VALERIE ; PATTURAJAN MEERA ; BAUMGARTNER JASON C ; GILBERT JENNIFER A ; SPADERNA STEVEN K</creator><creatorcontrib>JI WEIZHEN ; GUNTHER ERIK ; TCHERNEV VELIZAR T ; VERNET CORINE A.M ; BURGESS CATHERINE E ; CHANT JOHN S ; ORT TATIANA ; WOLENC ADAM R ; BERGHS CONSTANCE ; SHIMKETS RICHARD A ; GUO XIAOJIA SASHA ; LI LI ; SHENOY SURESH G ; STONE DAVID J ; EDINGER SHLOMIT R ; ZHONG MEI ; LIU XIAOHONG ; RASTELLI LUCA ; MILLET ISABELLE ; GANGOLLI ESHA A ; GORMAN LINDA ; PENA CAROL E.A ; SPYTEK KIMBERLY A ; FURTAK KATARZYNA ; ANDERSON DAVID W ; SMITHSON GLENNDA ; CASMAN STACIE J ; ELLERMAN KAREN ; MISHRA VISHNU ; BALLINGER ROBERT A ; TAUPIER RAYMOND J ; ZERHUSEN BRYAN D ; MACDOUGALL JOHN R ; MILLER CHARLES E ; PADIGARU MURALIDHARA ; GERLACH VALERIE ; PATTURAJAN MEERA ; BAUMGARTNER JASON C ; GILBERT JENNIFER A ; SPADERNA STEVEN K</creatorcontrib><description>The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.</description><edition>7</edition><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2004</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040304&DB=EPODOC&CC=US&NR=2004043929A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20040304&DB=EPODOC&CC=US&NR=2004043929A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>JI WEIZHEN</creatorcontrib><creatorcontrib>GUNTHER ERIK</creatorcontrib><creatorcontrib>TCHERNEV VELIZAR T</creatorcontrib><creatorcontrib>VERNET CORINE A.M</creatorcontrib><creatorcontrib>BURGESS CATHERINE E</creatorcontrib><creatorcontrib>CHANT JOHN S</creatorcontrib><creatorcontrib>ORT TATIANA</creatorcontrib><creatorcontrib>WOLENC ADAM R</creatorcontrib><creatorcontrib>BERGHS CONSTANCE</creatorcontrib><creatorcontrib>SHIMKETS RICHARD A</creatorcontrib><creatorcontrib>GUO XIAOJIA SASHA</creatorcontrib><creatorcontrib>LI LI</creatorcontrib><creatorcontrib>SHENOY SURESH G</creatorcontrib><creatorcontrib>STONE DAVID J</creatorcontrib><creatorcontrib>EDINGER SHLOMIT R</creatorcontrib><creatorcontrib>ZHONG MEI</creatorcontrib><creatorcontrib>LIU XIAOHONG</creatorcontrib><creatorcontrib>RASTELLI LUCA</creatorcontrib><creatorcontrib>MILLET ISABELLE</creatorcontrib><creatorcontrib>GANGOLLI ESHA A</creatorcontrib><creatorcontrib>GORMAN LINDA</creatorcontrib><creatorcontrib>PENA CAROL E.A</creatorcontrib><creatorcontrib>SPYTEK KIMBERLY A</creatorcontrib><creatorcontrib>FURTAK KATARZYNA</creatorcontrib><creatorcontrib>ANDERSON DAVID W</creatorcontrib><creatorcontrib>SMITHSON GLENNDA</creatorcontrib><creatorcontrib>CASMAN STACIE J</creatorcontrib><creatorcontrib>ELLERMAN KAREN</creatorcontrib><creatorcontrib>MISHRA VISHNU</creatorcontrib><creatorcontrib>BALLINGER ROBERT A</creatorcontrib><creatorcontrib>TAUPIER RAYMOND J</creatorcontrib><creatorcontrib>ZERHUSEN BRYAN D</creatorcontrib><creatorcontrib>MACDOUGALL JOHN R</creatorcontrib><creatorcontrib>MILLER CHARLES E</creatorcontrib><creatorcontrib>PADIGARU MURALIDHARA</creatorcontrib><creatorcontrib>GERLACH VALERIE</creatorcontrib><creatorcontrib>PATTURAJAN MEERA</creatorcontrib><creatorcontrib>BAUMGARTNER JASON C</creatorcontrib><creatorcontrib>GILBERT JENNIFER A</creatorcontrib><creatorcontrib>SPADERNA STEVEN K</creatorcontrib><title>Novel proteins and nucleic acids encoding same</title><description>The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2004</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDzyy9LzVEoKMovSc3MK1ZIzEtRyCtNzknNTFZITM5MKVZIzUvOT8nMS1coTsxN5WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8aHBRgYGJgYmxpZGlo6GxsSpAgCQcytK</recordid><startdate>20040304</startdate><enddate>20040304</enddate><creator>JI WEIZHEN</creator><creator>GUNTHER ERIK</creator><creator>TCHERNEV VELIZAR T</creator><creator>VERNET CORINE A.M</creator><creator>BURGESS CATHERINE E</creator><creator>CHANT JOHN S</creator><creator>ORT TATIANA</creator><creator>WOLENC ADAM R</creator><creator>BERGHS CONSTANCE</creator><creator>SHIMKETS RICHARD A</creator><creator>GUO XIAOJIA SASHA</creator><creator>LI LI</creator><creator>SHENOY SURESH G</creator><creator>STONE DAVID J</creator><creator>EDINGER SHLOMIT R</creator><creator>ZHONG 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GUNTHER ERIK ; TCHERNEV VELIZAR T ; VERNET CORINE A.M ; BURGESS CATHERINE E ; CHANT JOHN S ; ORT TATIANA ; WOLENC ADAM R ; BERGHS CONSTANCE ; SHIMKETS RICHARD A ; GUO XIAOJIA SASHA ; LI LI ; SHENOY SURESH G ; STONE DAVID J ; EDINGER SHLOMIT R ; ZHONG MEI ; LIU XIAOHONG ; RASTELLI LUCA ; MILLET ISABELLE ; GANGOLLI ESHA A ; GORMAN LINDA ; PENA CAROL E.A ; SPYTEK KIMBERLY A ; FURTAK KATARZYNA ; ANDERSON DAVID W ; SMITHSON GLENNDA ; CASMAN STACIE J ; ELLERMAN KAREN ; MISHRA VISHNU ; BALLINGER ROBERT A ; TAUPIER RAYMOND J ; ZERHUSEN BRYAN D ; MACDOUGALL JOHN R ; MILLER CHARLES E ; PADIGARU MURALIDHARA ; GERLACH VALERIE ; PATTURAJAN MEERA ; BAUMGARTNER JASON C ; GILBERT JENNIFER A ; SPADERNA STEVEN 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SASHA</au><au>LI LI</au><au>SHENOY SURESH G</au><au>STONE DAVID J</au><au>EDINGER SHLOMIT R</au><au>ZHONG MEI</au><au>LIU XIAOHONG</au><au>RASTELLI LUCA</au><au>MILLET ISABELLE</au><au>GANGOLLI ESHA A</au><au>GORMAN LINDA</au><au>PENA CAROL E.A</au><au>SPYTEK KIMBERLY A</au><au>FURTAK KATARZYNA</au><au>ANDERSON DAVID W</au><au>SMITHSON GLENNDA</au><au>CASMAN STACIE J</au><au>ELLERMAN KAREN</au><au>MISHRA VISHNU</au><au>BALLINGER ROBERT A</au><au>TAUPIER RAYMOND J</au><au>ZERHUSEN BRYAN D</au><au>MACDOUGALL JOHN R</au><au>MILLER CHARLES E</au><au>PADIGARU MURALIDHARA</au><au>GERLACH VALERIE</au><au>PATTURAJAN MEERA</au><au>BAUMGARTNER JASON C</au><au>GILBERT JENNIFER A</au><au>SPADERNA STEVEN K</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Novel proteins and nucleic acids encoding same</title><date>2004-03-04</date><risdate>2004</risdate><abstract>The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE |
| title | Novel proteins and nucleic acids encoding same |
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