Ubiquitin fusion-based vaccine system

Disclosed are epitope-containing heat shock fusion proteins, DNA constructs encoding such fusion proteins, and methods of use. More specifically, disclosed are ubiquitin fusion proteins comprising ubiquitin fused to a plurality of identical or non-identical epitopes at specified locations.

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Bibliographische Detailangaben
Hauptverfasser: TRAMONTANO ALFONSO, LOHNAS GERALD L, PILON APRILE L, KENTEN JOHN H, ROBERTS STEVEN F
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed are epitope-containing heat shock fusion proteins, DNA constructs encoding such fusion proteins, and methods of use. More specifically, disclosed are ubiquitin fusion proteins comprising ubiquitin fused to a plurality of identical or non-identical epitopes at specified locations.