Succinimide and maleimide derivatives and their use as topoisomerase II catalytic inhibitors

Maleimide and succinimide derivatives were found to be effective topoisomerase II catalytic inhibitors. Due to this property, the maleimide and succinimide derivatives were investigated for their use as cytostatic agents and thus in the treatment of cancer. The compounds of the invention can be used...

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Hauptverfasser:	CARSTENSEN ELISABETH VANG, SEHESTED MAXVELL, CREIGHTON ANDREW, JENSEN PETER BUHL, SOKILDE BIRGITTE, JENSEN LARS HOLLUND, LANGER SEPPO W
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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