1,4 substituted piperidinyl NMDA/NR2B antagonists

Novel piperidinyl compounds substituted in the 1- and 4-positions are effective as NMDA NR2B antagonists useful for relieving pain.

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Hauptverfasser: KULAGOWSKI JANUSZ, WHITTER WILLIE, HUSCROFT IAN, THOMPSON WAYNE, MUNSON PETER M, CLAREMON DAVID A
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creator KULAGOWSKI JANUSZ
WHITTER WILLIE
HUSCROFT IAN
THOMPSON WAYNE
MUNSON PETER M
CLAREMON DAVID A
description Novel piperidinyl compounds substituted in the 1- and 4-positions are effective as NMDA NR2B antagonists useful for relieving pain.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 1,4 substituted piperidinyl NMDA/NR2B antagonists
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