Separation of micromolecules

Separation of micromolecules

This invention is directed to an apparatus and method for the separation of molecules, particularly micromolecules having a molecular mass of less than 5000 Dalton. The present invention is directed to an apparatus for separating micromolecules by electrophoretic separation, the apparatus comprising...

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Hauptverfasser: RYAN LUCY JANE, CONLAN BRENDON FRANCIS, GILBERT ANDREW MARK, NAIR CHENICHERI HARIHARAN
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PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
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creator RYAN LUCY JANE
CONLAN BRENDON FRANCIS
GILBERT ANDREW MARK
NAIR CHENICHERI HARIHARAN
description This invention is directed to an apparatus and method for the separation of molecules, particularly micromolecules having a molecular mass of less than 5000 Dalton. The present invention is directed to an apparatus for separating micromolecules by electrophoretic separation, the apparatus comprising: (a) an anode; (b) a cathode disposed relative to the anode so as to be adapted to generate an electric field in an electric field area therebetween upon application of a voltage potential between the anode and the cathode; (c) a separation membrane disposed in the electric field area; (d) a first restriction membrane disposed between the anode and the separation membrane so as to define a first interstitial volume therebetween; (e) a second restriction membrane disposed between the cathode and the separation membrane so as to define a second interstitial volume therebetween; and (f) means adapted to provide a sample constituent in a selected one of the first and second interstitial volumes; wherein upon application of the voltage potential, a selected separation product is removed from the sample constituent, thorough the separation membrane, and provided to the other of the first and second interstitial volumes, wherein a micromolecule is capable of being retained in at least one of the interstitial volumes, and wherein a micromolecule is capable of being retained in at least one of the interstitial volumes.
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The present invention is directed to an apparatus for separating micromolecules by electrophoretic separation, the apparatus comprising: (a) an anode; (b) a cathode disposed relative to the anode so as to be adapted to generate an electric field in an electric field area therebetween upon application of a voltage potential between the anode and the cathode; (c) a separation membrane disposed in the electric field area; (d) a first restriction membrane disposed between the anode and the separation membrane so as to define a first interstitial volume therebetween; (e) a second restriction membrane disposed between the cathode and the separation membrane so as to define a second interstitial volume therebetween; and (f) means adapted to provide a sample constituent in a selected one of the first and second interstitial volumes; wherein upon application of the voltage potential, a selected separation product is removed from the sample constituent, thorough the separation membrane, and provided to the other of the first and second interstitial volumes, wherein a micromolecule is capable of being retained in at least one of the interstitial volumes, and wherein a micromolecule is capable of being retained in at least one of the interstitial volumes.</description><edition>7</edition><language>eng</language><subject>PERFORMING OPERATIONS ; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL ; SEPARATION ; TRANSPORTING</subject><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20021017&amp;DB=EPODOC&amp;CC=US&amp;NR=2002148730A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20021017&amp;DB=EPODOC&amp;CC=US&amp;NR=2002148730A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RYAN LUCY JANE</creatorcontrib><creatorcontrib>CONLAN BRENDON FRANCIS</creatorcontrib><creatorcontrib>GILBERT ANDREW MARK</creatorcontrib><creatorcontrib>NAIR CHENICHERI HARIHARAN</creatorcontrib><title>Separation of micromolecules</title><description>This invention is directed to an apparatus and method for the separation of molecules, particularly micromolecules having a molecular mass of less than 5000 Dalton. 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subjects PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
SEPARATION
TRANSPORTING
title Separation of micromolecules
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