High purity (1R, 2S, 4R) -(-) -2- [ (2' -{N,N-dimethylamino} -ethoxy) ] -2- [phenyl] -1, 7,7 -tri - [methyl] -bicyclo [2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof and a process for the preparation of these compounds as well as medicaments containing 1 or more of these compounds and their use

High purity (1R, 2S, 4R) -(-) -2- [ (2' -{N,N-dimethylamino} -ethoxy) ] -2- [phenyl] -1, 7,7 -tri - [methyl] -bicyclo [2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof and a process for the preparation of these compounds as well as medicaments containing 1 or more of these compounds and their use

The invention relates to high purity (1R,2S,4R)-(-)-2-[ (2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-methyl -bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2'-{N,N-dimethylamino}-ethyl)]-1 ,7,7-tri-...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KRASZNAI GYORGY, BUDAI ZOLTAN, NAGY KALMAN, VERECZKEY GYORGYI DONATH, SZULAGYI JANOS, LUKACS GYULA, PORCS-MAKKAY MARTA, MEZEI TIBOR, SIMIG GYULA, NEMETH NORBERT, SZABO TIBOR
Format: Patent
Sprache:eng
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator KRASZNAI GYORGY
BUDAI ZOLTAN
NAGY KALMAN
VERECZKEY GYORGYI DONATH
SZULAGYI JANOS
LUKACS GYULA
PORCS-MAKKAY MARTA
MEZEI TIBOR
SIMIG GYULA
NEMETH NORBERT
SZABO TIBOR
description The invention relates to high purity (1R,2S,4R)-(-)-2-[ (2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-methyl -bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2'-{N,N-dimethylamino}-ethyl)]-1 ,7,7-tri-[methyl]-bicyclo[2.2.1]heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US2002040164A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US2002040164A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US2002040164A13</originalsourceid><addsrcrecordid>eNqNTz1LA0EQ1cJC1P_wwMIEbsPdGUwtQUmVItEqhDDZm-QW9naX3Q16iP_dSWJpYTPD-xzm-nI6M_sW4RBN7jGoFgXqZYHxYgg1UDJqhRUG9QPU17yYq8Z0nNveUmec_4YS4D_7IdZnZ2jZ9VZAVWBSTKByNBD-HBJ-a3SvrceqHtWjao2WQybHINcgtBQ70nzIRpO1PUjro7y1omvTgJrGZOMdEtmckFuO7HenLCFErzkl7Hw8KoI5UKSTX0xCJYb2XfAH1yRQwgdbe9wdN3KwYyed2rtMxhm3RwVp6nzkP-NyUzgTcUh8e3G1I5v47nffXNy_vrxNZ4qD33AK8pPjvHlf1mVZl-Oyeho_V4__c_0AOc-H1w</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>High purity (1R, 2S, 4R) -(-) -2- [ (2' -{N,N-dimethylamino} -ethoxy) ] -2- [phenyl] -1, 7,7 -tri - [methyl] -bicyclo [2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof and a process for the preparation of these compounds as well as medicaments containing 1 or more of these compounds and their use</title><source>esp@cenet</source><creator>KRASZNAI GYORGY ; BUDAI ZOLTAN ; NAGY KALMAN ; VERECZKEY GYORGYI DONATH ; SZULAGYI JANOS ; LUKACS GYULA ; PORCS-MAKKAY MARTA ; MEZEI TIBOR ; SIMIG GYULA ; NEMETH NORBERT ; SZABO TIBOR</creator><creatorcontrib>KRASZNAI GYORGY ; BUDAI ZOLTAN ; NAGY KALMAN ; VERECZKEY GYORGYI DONATH ; SZULAGYI JANOS ; LUKACS GYULA ; PORCS-MAKKAY MARTA ; MEZEI TIBOR ; SIMIG GYULA ; NEMETH NORBERT ; SZABO TIBOR</creatorcontrib><description>The invention relates to high purity (1R,2S,4R)-(-)-2-[ (2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-methyl -bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2'-{N,N-dimethylamino}-ethyl)]-1 ,7,7-tri-[methyl]-bicyclo[2.2.1]heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.</description><edition>7</edition><language>eng</language><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20020404&amp;DB=EPODOC&amp;CC=US&amp;NR=2002040164A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20020404&amp;DB=EPODOC&amp;CC=US&amp;NR=2002040164A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KRASZNAI GYORGY</creatorcontrib><creatorcontrib>BUDAI ZOLTAN</creatorcontrib><creatorcontrib>NAGY KALMAN</creatorcontrib><creatorcontrib>VERECZKEY GYORGYI DONATH</creatorcontrib><creatorcontrib>SZULAGYI JANOS</creatorcontrib><creatorcontrib>LUKACS GYULA</creatorcontrib><creatorcontrib>PORCS-MAKKAY MARTA</creatorcontrib><creatorcontrib>MEZEI TIBOR</creatorcontrib><creatorcontrib>SIMIG GYULA</creatorcontrib><creatorcontrib>NEMETH NORBERT</creatorcontrib><creatorcontrib>SZABO TIBOR</creatorcontrib><title>High purity (1R, 2S, 4R) -(-) -2- [ (2' -{N,N-dimethylamino} -ethoxy) ] -2- [phenyl] -1, 7,7 -tri - [methyl] -bicyclo [2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof and a process for the preparation of these compounds as well as medicaments containing 1 or more of these compounds and their use</title><description>The invention relates to high purity (1R,2S,4R)-(-)-2-[ (2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-methyl -bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2'-{N,N-dimethylamino}-ethyl)]-1 ,7,7-tri-[methyl]-bicyclo[2.2.1]heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNTz1LA0EQ1cJC1P_wwMIEbsPdGUwtQUmVItEqhDDZm-QW9naX3Q16iP_dSWJpYTPD-xzm-nI6M_sW4RBN7jGoFgXqZYHxYgg1UDJqhRUG9QPU17yYq8Z0nNveUmec_4YS4D_7IdZnZ2jZ9VZAVWBSTKByNBD-HBJ-a3SvrceqHtWjao2WQybHINcgtBQ70nzIRpO1PUjro7y1omvTgJrGZOMdEtmckFuO7HenLCFErzkl7Hw8KoI5UKSTX0xCJYb2XfAH1yRQwgdbe9wdN3KwYyed2rtMxhm3RwVp6nzkP-NyUzgTcUh8e3G1I5v47nffXNy_vrxNZ4qD33AK8pPjvHlf1mVZl-Oyeho_V4__c_0AOc-H1w</recordid><startdate>20020404</startdate><enddate>20020404</enddate><creator>KRASZNAI GYORGY</creator><creator>BUDAI ZOLTAN</creator><creator>NAGY KALMAN</creator><creator>VERECZKEY GYORGYI DONATH</creator><creator>SZULAGYI JANOS</creator><creator>LUKACS GYULA</creator><creator>PORCS-MAKKAY MARTA</creator><creator>MEZEI TIBOR</creator><creator>SIMIG GYULA</creator><creator>NEMETH NORBERT</creator><creator>SZABO TIBOR</creator><scope>EVB</scope></search><sort><creationdate>20020404</creationdate><title>High purity (1R, 2S, 4R) -(-) -2- [ (2' -{N,N-dimethylamino} -ethoxy) ] -2- [phenyl] -1, 7,7 -tri - [methyl] -bicyclo [2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof and a process for the preparation of these compounds as well as medicaments containing 1 or more of these compounds and their use</title><author>KRASZNAI GYORGY ; BUDAI ZOLTAN ; NAGY KALMAN ; VERECZKEY GYORGYI DONATH ; SZULAGYI JANOS ; LUKACS GYULA ; PORCS-MAKKAY MARTA ; MEZEI TIBOR ; SIMIG GYULA ; NEMETH NORBERT ; SZABO TIBOR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US2002040164A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><toplevel>online_resources</toplevel><creatorcontrib>KRASZNAI GYORGY</creatorcontrib><creatorcontrib>BUDAI ZOLTAN</creatorcontrib><creatorcontrib>NAGY KALMAN</creatorcontrib><creatorcontrib>VERECZKEY GYORGYI DONATH</creatorcontrib><creatorcontrib>SZULAGYI JANOS</creatorcontrib><creatorcontrib>LUKACS GYULA</creatorcontrib><creatorcontrib>PORCS-MAKKAY MARTA</creatorcontrib><creatorcontrib>MEZEI TIBOR</creatorcontrib><creatorcontrib>SIMIG GYULA</creatorcontrib><creatorcontrib>NEMETH NORBERT</creatorcontrib><creatorcontrib>SZABO TIBOR</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KRASZNAI GYORGY</au><au>BUDAI ZOLTAN</au><au>NAGY KALMAN</au><au>VERECZKEY GYORGYI DONATH</au><au>SZULAGYI JANOS</au><au>LUKACS GYULA</au><au>PORCS-MAKKAY MARTA</au><au>MEZEI TIBOR</au><au>SIMIG GYULA</au><au>NEMETH NORBERT</au><au>SZABO TIBOR</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>High purity (1R, 2S, 4R) -(-) -2- [ (2' -{N,N-dimethylamino} -ethoxy) ] -2- [phenyl] -1, 7,7 -tri - [methyl] -bicyclo [2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof and a process for the preparation of these compounds as well as medicaments containing 1 or more of these compounds and their use</title><date>2002-04-04</date><risdate>2002</risdate><abstract>The invention relates to high purity (1R,2S,4R)-(-)-2-[ (2'-{N,N-dimethylamino}-ethoxy)]-2-[phenyl]-1,7,7-tri-methyl -bicyclo[2.2.1]heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2% of (1R,3S,4R)-3-[(2'-{N,N-dimethylamino}-ethyl)]-1 ,7,7-tri-[methyl]-bicyclo[2.2.1]heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US2002040164A1
source esp@cenet
title High purity (1R, 2S, 4R) -(-) -2- [ (2' -{N,N-dimethylamino} -ethoxy) ] -2- [phenyl] -1, 7,7 -tri - [methyl] -bicyclo [2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof and a process for the preparation of these compounds as well as medicaments containing 1 or more of these compounds and their use
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-11T18%3A15%3A33IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KRASZNAI%20GYORGY&rft.date=2002-04-04&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS2002040164A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true